SCM308
3dGRO® Lung Organoid Maturation Medium
Serum-free ready-to-use media used to differentiate lung bud organoids (LBOs) into mature branching lung organoids.
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General description
The 3dGRO Lung Organoid Maturation Medium is a chemically defined/serum-free ready-to-use media used to differentiate lung bud organoids (LBOs) into mature lung organoids that structurally resemble the in vivo branching airway and early alveolar structures. Large numbers of mature lung organoids may be generated that express appropriate markers indicative of multiple cell types found in the mature lung and airways including: SFTPB and SFTPC, MUC5AC, EpCAM, Sox9, Nkx2.1, acetyl-a-tubulin and Vimentin. Additionally, the mature lung organoids express ACE2 and TMPRSS2 for SARS-CoV2 viral research. The 3dGRO Lung Organoid Maturation Medium is a component of the 3dGRO Human Lung Organoid Culture System which can be used to differentiate human iPS cells into mature lung organoids that structurally resemble the in vivo branching airway and early alveolar structures.The 3dGRO® Human Lung Organoid Culture System includes (all sold separately):
- Definitive Endoderm Induction Medium (SCM302)
- Anterior Foregut Endoderm Induction Medium I (SCM305)
- Anterior Foregut Endoderm Induction Medium II (SCM306)
- 3dGRO® Lung Organoid Branching Medium (SCM307)
- 3dGRO® Lung Organoid Maturation Medium (SCM308)
Human iPSC Derived AFE Progenitors (SCC301)
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Articles
Lung organoids are valuable 3D models for human lung development and respiratory diseases. The 3dGRO™ differentiation protocol generates organoids from human iPSCs in 4 steps.
Organoid culture FAQs. Learn how to culture and analyze organoids following established 3D cell culture protocols. Tips and tricks.
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Our broad range of the most trusted tools for cell culture includes stringently sourced and tested FBS, established media formulations, and sterile labware. Cutting-edge techniques using stem cells and 3D matrices are enabled by organoids, hydrogels, culture scaffolds, and bioinks for 3D bioprinting.
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