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Key Documents

09-1970

Sigma-Aldrich

Ethyl 4-hydroxybenzoate

SAJ first grade, ≥99.0%

Synonym(s):

Ethylparaben

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About This Item

Linear Formula:
HOC6H4CO2C2H5
CAS Number:
Molecular Weight:
166.17
Beilstein/REAXYS Number:
1101972
MDL number:
UNSPSC Code:
12352108
PubChem Substance ID:

Pricing and availability is not currently available.

grade

SAJ first grade

assay

≥99.0%

availability

available only in Japan

bp

297-298 °C (lit.)

mp

114-117 °C (lit.)

SMILES string

CCOC(=O)c1ccc(O)cc1

InChI

1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3

InChI key

NUVBSKCKDOMJSU-UHFFFAOYSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Sawsan El Hussein et al.
Experimental dermatology, 16(10), 830-836 (2007-09-12)
Concern is continuously raised about the safety of parabens which are present in most of the cosmetic preparations. In this investigation, methyl-, ethyl-, propyl- and butyl paraben (MP, EP, PP, BP), in a commercial cosmetic lotion, were deposited on human
S Nicoli et al.
Journal of pharmaceutical sciences, 97(11), 4830-4839 (2008-03-05)
This work aims at investigating the nicotinamide (NA)-ethyl-paraben (EP) binary system both in solution and in the solid state. In particular, the apparent EP solubility in water was studied in the presence of different NA concentrations (between 0.28 and 1.64
Shinshi Oishi
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 42(11), 1845-1849 (2004-09-08)
Parabens are alkyl esters of p-hydroxybenzoic acid widely used as preservatives in foodstuffs, cosmetics toiletries and pharmaceuticals. These compounds are known to exert a weak estrogenic activity in estrogen receptor assays in vitro. In addition butyl and propyl parabens show
K L Pedersen et al.
Pharmacology & toxicology, 86(3), 110-113 (2001-02-07)
The widely used phenolic preservatives ethylparaben, propylparaben, butylparaben and their common metabolite p-hydroxybenzoic acid were tested for their ability to evoke an oestrogenic response in vivo. Yolk protein induction in sexually immature rainbow trout was used as an oestrogen-specific endpoint
Antonia M Calafat et al.
Environmental health perspectives, 118(5), 679-685 (2010-01-09)
Parabens are widely used as antimicrobial preservatives in cosmetics, -pharmaceuticals, and food and beverage processing. We assessed exposure to methyl, ethyl, propyl, and butyl parabens in a representative sample of persons >or= 6 years of age in the U.S. general

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