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Sigma-Aldrich

Tetrahydrofuran

≥99.7% (GC), contains no stabilizer, suitable for HPLC

Synonym(s):

THF, Butylene oxide, Oxolane, Tetramethylene oxide

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About This Item

Empirical Formula (Hill Notation):
C4H8O
CAS Number:
Molecular Weight:
72.11
Beilstein/REAXYS Number:
102391
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:

product name

Tetrahydrofuran, suitable for HPLC, contains no stabilizer

vapor density

2.5 (vs air)

vapor pressure

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

assay

≥99.7% (GC)

form

liquid

autoignition temp.

610 °F

does not contain

stabilizer

expl. lim.

1.8-11.8 %

availability

available only in Japan

technique(s)

HPLC: suitable

refractive index

n20/D 1.407 (lit.)

pH

~7

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

density

0.889 g/mL at 25 °C (lit.)

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

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Related Categories

Application


  • Complexation and disproportionation of group 4 metal (alkoxy) halides with phosphine oxides.: This research utilizes tetrahydrofuran (THF) as a solvent to study the complexation and disproportionation reactions of group 4 metal halides, providing insights into coordination chemistry and potential applications in materials science (Seno et al., 2024).

  • Synthesis of Room Temperature Curable Polymer Binder Mixed with Polymethyl Methacrylate and Urethane Acrylate for High-Strength and Improved Transparency.: THF is used as a solvent in the synthesis of advanced polymer binders, highlighting its role in developing materials with enhanced mechanical properties and optical clarity for industrial applications (Lee et al., 2024).

  • Fabrication of Polypyrrole Hollow Nanospheres by Hard-Template Method for Supercapacitor Electrode Material.: This study employs THF in the fabrication process of polypyrrole nanospheres, demonstrating its importance in the production of high-performance supercapacitor electrode materials (Hong et al., 2024).

  • Promoting Cross-Link Reaction of Polymers by the Matrix-Filler Interface Effect: Role of Coupling Agents and Intermediate Linkers.: The use of THF as a solvent facilitates the cross-linking reactions in polymers, enhancing their mechanical stability and expanding their applications in various fields of materials science (Huang et al., 2024).

  • Solvent Regulation Induced Cathode Aggregation-Induced Electrochemiluminescence of Tetraphenylethylene Nanoaggregates for Ultrasensitive Zearalenone Analysis.: THF is critical in the solvent regulation process for electrochemiluminescence assays, significantly improving the sensitivity of analytical techniques for detecting environmental contaminants (Chen et al., 2024).

recommended

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system, Respiratory system

supp_hazards

wgk_germany

WGK 1

flash_point_f

5.9 °F

flash_point_c

-14.5 °C


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ryan D Pensack et al.
Journal of the American Chemical Society, 137(21), 6790-6803 (2015-05-07)
We compare the singlet fission dynamics of five pentacene derivatives precipitated to form nanoparticles. Two nanoparticle types were distinguished by differences in their solid-state order and kinetics of triplet formation. Nanoparticles that comprise primarily weakly coupled chromophores lack the bulk
Luca Chiari et al.
The Journal of chemical physics, 138(7), 074301-074301 (2013-03-01)
We present total, elastic, and inelastic cross sections for positron and electron scattering from tetrahydrofuran (THF) in the energy range between 1 and 5000 eV. Total cross sections (TCS), positronium formation cross sections, the summed inelastic integral cross sections (ICS)
Crispin Lichtenberg et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(44), 15797-15805 (2015-09-17)
The reactivity of the all-ferrous FeN heterocubane [Fe4 (Ntrop)4 ] (1) with i) Brønsted acids, ii) σ-donors, iii) σ-donors/π-acceptors, and iv) one-electron oxidants has been investigated (trop = 5H-dibenzo[a,d]cyclo-hepten-5-yl). 1 showed self-re-assembling after reactions with i) and proved surprisingly inert in reactions with ii)
Tetrahydrofuran-containing macrolides: a fascinating gift from the deep sea.
Adriana Lorente et al.
Chemical reviews, 113(7), 4567-4610 (2013-03-20)
Han Yan et al.
Advanced materials (Deerfield Beach, Fla.), 27(23), 3484-3491 (2015-05-06)
Polymer solar cells are fabricated with systematic variation of the phase purity. Photovoltaic tests demonstrate that devices with ca. 10% of mixed phases outperform pure-phase devices. Photophysical studies reveal the effects of mixed phase on charge generation and recombination. These

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