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00307

Sigma-Aldrich

ADA

BioUltra, ≥99.0% (T)

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Synonym(s):
N-(2-Acetamido)iminodiacetic acid, N-(Carbamoylmethyl)iminodiacetic acid
Linear Formula:
H2NCOCH2N(CH2CO2H)2
CAS Number:
Molecular Weight:
190.15
Beilstein/REAXYS Number:
1787181
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

product line

BioUltra

Quality Level

assay

≥99.0% (T)

form

powder or crystals

impurities

insoluble matter, passes filter test

ign. residue

≤0.1%

loss

≤0.5% loss on drying, 20 °C (HV)

pH

1.5-3.0 (25 °C, 0.01 M in H2O)

useful pH range

6.0-7.2

pKa (25 °C)

6.6

mp

219 °C (dec.) (lit.)

solubility

H2O: 0.05 M, clear, colorless

anion traces

chloride (Cl-): ≤1000 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤500 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

0.05 M in H2O

UV absorption

λ: 260 nm Amax: 0.20
λ: 280 nm Amax: 0.05

SMILES string

NC(=O)CN(CC(O)=O)CC(O)=O

InChI

1S/C6H10N2O5/c7-4(9)1-8(2-5(10)11)3-6(12)13/h1-3H2,(H2,7,9)(H,10,11)(H,12,13)

InChI key

QZTKDVCDBIDYMD-UHFFFAOYSA-N

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1 of 4

This Item
A98832348778.14165
vibrant-m

00307

ADA

Premium Grade
vibrant-m

A9883

ADA

-
vibrant-m

8.14165

Iminodiacetic acid

-
assay

≥99.0% (T)

assay

≥98% (titration)

assay

98%

assay

≥96.0% (acidimetric)

form

powder or crystals

form

powder

form

solid

form

crystals

impurities

insoluble matter, passes filter test

impurities

-

impurities

-

impurities

-

ign. residue

≤0.1%

ign. residue

-

ign. residue

-

ign. residue

-

loss

≤0.5% loss on drying, 20 °C (HV)

loss

-

loss

-

loss

-

Application

ADA, or N-(2-Acetamido)iminodiacetic acid, can be used to study biological buffers and zwitterionic compounds. ADA has been used in a study to describe the application of scanning capacitively coupled contactless conductivity detection (SC(4)D) for the determination of pH dependant behaviour of two aminopolycarboxylates immobilised onto the surface of a monolithic capillary column.
Biological buffer component with sodium hydroxide and sodium chloride (pH 5.67-7.57, useful pH range 6.4-7.4). Used to prepare immobilized pH gradients.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Identification of metallothionein isoforms with capillary zone electrophoresis using a polyacrylamide-coated tube
Minami, T., et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 685, 353-359 (1996)
Birte M Gerken et al.
Analytical chemistry, 77(19), 6113-6117 (2005-10-01)
A novelly developed tweezing-adsorptive bubble separation (ABS) method for the enrichment of metalloenzymes (laccase C and horseradish peroxidase) is introduced. The method is based on the chelation of the enzymes' active center and can also be applied for analysis. N-(2-acetamido)iminodiacetic
Eoin Gillespie et al.
Journal of separation science, 32(15-16), 2659-2667 (2009-07-09)
The application of scanning capacitively coupled contactless conductivity detection (SC(4)D) for the determination of pH dependant behaviour of two aminopolycarboxylates immobilised onto the surface of a monolithic capillary column is described. The use of SC(4)D to visualise changes in conductivity
Yin-Cheng Hsieh et al.
The Journal of biological chemistry, 288(42), 30645-30658 (2013-09-06)
Lysine carbamylation, a post-translational modification, facilitates metal coordination for specific enzymatic activities. We have determined structures of the vertebrate dihydropyrimidinase from Tetraodon nigroviridis (TnDhp) in various states: the apoenzyme as well as two forms of the holoenzyme with one and
D M Bers et al.
The American journal of physiology, 260(5 Pt 1), C900-C909 (1991-05-01)
Extracellular Ca (Cao) depletions that occur during cardiac muscle contractions are indicative of net Ca entry. Buffering Cao concentration ([Ca]o) with citrate can limit the magnitude of these Cao depletions [e.g., Shattock and Bers. Am. J. Physiol. 256 (Cell Physiol.

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