02390

1,2-Ethanedithiol

≥98.0% (GC)

• Synonym(s): 1,2-Dimercaptoethane, Dithioglycol, Ethylene mercaptan
• Linear Formula: HSCH₂CH₂SH
• CAS Number: 540-63-6
• Molecular Weight: 94.20
• Beilstein/REAXYS Number: 505946
• EC Number: 208-752-3
• MDL number: MFCD00004892
• UNSPSC Code: 12352100
• PubChem Substance ID: 329747425
• NACRES: NA.22

Properties

• vapor density: >1 (vs air)
• Quality Level: 200
• vapor pressure: 4.8 mmHg ( 20 °C)
• assay: ≥98.0% (GC)
• form: liquid
• refractive index: n20/D 1.558 (lit.); n20/D 1.558
• bp: 144-146 °C (lit.)
• mp: −41 °C (lit.)
• density: 1.123 g/mL at 25 °C (lit.)
• functional group: thiol
• SMILES string: SCCS
• InChI: 1S/C2H6S2/c3-1-2-4/h3-4H,1-2H2
• InChI key: VYMPLPIFKRHAAC-UHFFFAOYSA-N

Description

General description

1,2-Ethanedithiol (EDT) is an organosulfur compound that is used as an organic building block in chemical synthesis. It is also used as a ligand for metal ions to prepare metal complexes.

Application

1,2-Ethanedithiol can be used to synthesize:      

• 1,3-Dithiolanes by reacting with aldehydes or ketones.
• Dithiazepan-3-yl-alkanoic acids by cyclocondensation reaction with amino acids and formaldehyde.
• EDT can also be used as a scavenger in solid phase peptide synthesis for the efficient deprotection of the peptide resin.

Safety Information

• pictograms: GHS02,GHS06
• signalword: Danger
• hcodes: H226,H301,H310 + H330
• pcodes: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 3
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 111.2 °F - closed cup
• flash_point_c: 44 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter