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Oenothein B

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C68H48O44
CAS Number:
Molecular Weight:
1569.08
UNSPSC Code:
85151701
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥80% (HPLC)

shelf life

limited shelf life, expiry date on the label

application(s)

food and beverages

format

neat

storage temp.

2-8°C

InChI

1S/C68H50O44/c69-22-1-14(2-23(70)39(22)79)59(93)109-56-52(92)68(112-61(95)16-5-26(73)41(81)27(74)6-16)106-34-13-103-63(97)20-11-32(46(86)50(90)38(20)37-19(64(98)107-54(34)56)9-30(77)44(84)49(37)89)104-53-21(10-31(78)45(85)51(53)91)66(100)111-58-57(110-60(94)15-3-24(71)40(80)25(72)4-15)55-33(105-67(58)101)12-102-62(96)17-7-28(75)42(82)47(87)35(17)36-18(65(99)108-55)8-29(76)43(83)48(36)88/h1-11,33-34,52,54-58,67-92,101H,12-13H2

InChI key

SHYSVHSGJVNSLX-UHFFFAOYSA-N

General description

Oenothein B is a dimeric ellagitannin compound which is found commonly in genusOenothera.

Application

Oenothein B may be used as a reference standard for the determination of oenothein B in aqueous extracts of Epilobii angustifolli herba and Epilobium angustifolium L. by high performance thin-layer chromatography (HPTLC)-densitometry, in plant materials by HPLC combined with diode array detector (DAD) and mass spectrometry (MS) and in Eucalyptus globulus leaves by HPLC-DAD coupled to electrospray ionization (EIS) MS.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Hideharu Maruta et al.
Biological & pharmaceutical bulletin, 30(3), 447-450 (2007-03-03)
The formation of ATP produced from poly(ADP-ribose) [(ADP-R)n] has been suggested to be required to repair damaged DNA. Here we investigate whether this ATP is involved in DNA replication processes during DNA repair. Poly(ADP-ribosyl)ated mid-S phase cell nuclei, which were
C C Wang et al.
Cancer letters, 140(1-2), 195-200 (1999-07-14)
We evaluated the antitumor activities of four macrocyclic hydrolyzable tannin dimers, cuphiin D1, cuphiin D2, oenothein B and woodfordin C isolated from Cuphea hyssopifolia (Lythraceae). All significantly inhibited the growth of the human carcinoma cell lines KB, HeLa, DU-145, Hep
D Lesuisse et al.
Journal of natural products, 59(5), 490-492 (1996-05-01)
Several extracts from Epilobium parviflorum, a plant used in Central Europe for the treatment of prostate disorders, were evaluated in a biochemical assay with 5-alpha-reductase. The aqueous extract displaying inhibition of the enzyme was analyzed, the fraction responsible for this
Barbara Hevesi Tóth et al.
Journal of pharmaceutical and biomedical analysis, 49(1), 26-31 (2008-11-18)
Epilobium species (Onagraceae) are commonly used herbal remedies in traditional, adjuvant therapy of benignus prostate hyperplasia (BPH), however the pharmacological and clinical standardization of commercially available Epilobii herba (willow-herb) remains difficult. Willow-herb products usually consist of mixtures from various species
K Aoki et al.
Biochemical and biophysical research communications, 210(2), 329-337 (1995-05-16)
Oenothein B, a macrocircular dimeric ellagitannin, was found to be a potent and specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B suppressed glucocorticoid-sensitive mouse mammary tumor virus (MMTV) transcription in 34I cells. This suppression was accompanied by inhibition of glucocorticoid-induced endogeneous

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