03951
N-Ethylformamide
≥99.0% (GC)
Synonym(s):
N-Formylethylamine
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About This Item
Linear Formula:
HCONHC2H5
CAS Number:
Molecular Weight:
73.09
Beilstein/REAXYS Number:
1737860
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
100
500
assay
≥99.0% (GC)
form
liquid
refractive index
n20/D 1.432
bp
202-204 °C
density
0.950 g/mL at 20 °C (lit.)
SMILES string
CCNC=O
InChI
1S/C3H7NO/c1-2-4-3-5/h3H,2H2,1H3,(H,4,5)
InChI key
KERBAAIBDHEFDD-UHFFFAOYSA-N
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Gloves
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M R Del Carratore et al.
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Chemical research in toxicology, 3(4), 357-362 (1990-07-01)
Hepatotoxic formamides such as N-methylformamide (NMF) and N,N-dimethylformamide (DMF) are metabolized in vivo to N-acetyl-S-(N-methylcarbamoyl)cysteine via oxidation at the formyl carbon, which yields a reactive intermediate. The hypothesis was tested that this biotransformation route can be studied in vitro with
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The Saccharomyces cerevisiae DGK1 gene encodes a diacylglycerol kinase enzyme that catalyzes the formation of phosphatidate from diacylglycerol. Unlike the diacylglycerol kinases from bacteria, plants, and animals, the yeast enzyme utilizes CTP, instead of ATP, as the phosphate donor in
S P Langdon et al.
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The induction of terminal differentiation in tumour cells represents a possible therapeutic strategy for treating cancer. The alkylformamides are 1 group of experimental compounds which have been shown to induce terminal differentiation in human HL-60 leukemia and murine Friend erythroleukemia
P Kestell et al.
The Journal of pharmacology and experimental therapeutics, 240(1), 265-270 (1987-01-01)
The hepatotoxicity and metabolism of the following close analogs of the hepatotoxic antitumor agent N-methylformamide (NMF) were investigated in CBA/CA mice: N-ethylformamide (NEF), dimethylformamide (DMF), formamide and N-methylacetamide (NMA). Apart from NMF only NEF was potently hepatotoxic as measured by
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