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112763

Sigma-Aldrich

Diphenylamine

ReagentPlus®, 99%

Synonym(s):

N-Phenylbenzenamine, DBA, DFA, DPA

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About This Item

Linear Formula:
(C6H5)2NH
CAS Number:
Molecular Weight:
169.22
Beilstein/REAXYS Number:
508755
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

vapor density

5.82 (vs air)

Quality Level

vapor pressure

1 mmHg ( 108 °C)

product line

ReagentPlus®

assay

99%

autoignition temp.

1175 °F

bp

302 °C (lit.)

mp

50-53 °C (lit.)

solubility

water: insoluble

SMILES string

N(c1ccccc1)c2ccccc2

InChI

1S/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H

InChI key

DMBHHRLKUKUOEG-UHFFFAOYSA-N

Gene Information

human ... UGT1A4(54657)

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General description

Diphenylamine, a secondary aromatic amine, is an N-substituted derivative of aniline.

Application

Diphenylamine may be used in the preparation of diphenylamine reagent, which is employed for the quantitative estimation of nucleic acid (DNA) from various biological sources by colorimetric method. It may be used in the preparation of poly(diphenylamine), via electrochemical and chemical polymerization methods. It can also be used as an internal standard in the determination of hair nicotine via gas chromatography coupled with mass spectrometry.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

target_organs

Kidney,Liver,spleen

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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"Determination of hair nicotine by gas chromatography?mass spectrometry"
Man NC, et al
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 877(03), 339-342 (2009)
An improved diphenylamine method for the estimation of deoxyribonucleic acid.
Giles KW and Myers A.
Nature, 206(4979) , 93-93 (1965)
Soluble and methane sulfonic acid doped poly (diphenylamine)-synthesis and characterization.
Wen T-C, et al.
Materials Letters, 57(2), 280-290 (2002)
Walter J Jessen et al.
The Journal of clinical investigation, 123(1), 340-347 (2012-12-12)
Neurofibromatosis type 1 (NF1) patients develop benign neurofibromas and malignant peripheral nerve sheath tumors (MPNST). These incurable peripheral nerve tumors result from loss of NF1 tumor suppressor gene function, causing hyperactive Ras signaling. Activated Ras controls numerous downstream effectors, but
Sarah G Pati et al.
Environmental science & technology, 46(21), 11844-11853 (2012-09-29)
Dioxygenation of aromatic rings is frequently the initial step of biodegradation of organic subsurface pollutants. This process can be tracked by compound-specific isotope analysis to assess the extent of contaminant transformation, but the corresponding isotope effects, especially for dioxygenation of

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