20959

Cesium carbonate

puriss. p.a., ≥99.0%

• Synonym(s): Carbonic acid dicesium
• Linear Formula: Cs₂CO₃
• CAS Number: 534-17-8
• Molecular Weight: 325.82
• Beilstein/REAXYS Number: 4546405
• EC Number: 208-591-9
• MDL number: MFCD00010957
• UNSPSC Code: 12352301
• PubChem Substance ID: 329752061
• NACRES: NA.22

Properties

• grade: puriss. p.a.
• Quality Level: 100
• assay: ≥99.0% (T); ≥99.0%
• impurities: ≤0.002% total nitrogen (N)
• mp: 610 °C (dec.) (lit.)
• anion traces: chloride (Cl^-): ≤20 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• SMILES string: [Cs+].[Cs+].[O-]C([O-])=O
• InChI: 1S/CH2O3.2Cs/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2
• InChI key: FJDQFPXHSGXQBY-UHFFFAOYSA-L

Description

General description

Cesium carbonate is an inorganic base generally used in C, N, O-arylation and alkylation reactions. It is also used in six-membered annulation, cross-coupling, intramolecular and intermolecular cyclizations, aza-Henry reaction, Horner-Emmons cyclization, and cycloaddition reactions.

Application

Cesium carbonate, an alkali metal carbonate, is a commonly used inorganic base in organic reactions.
Synthetic applications:

• As a catalyst to synthesize quinazoline-2,4(1H,3H)-diones from substituted 2-aminobenzonitriles and carbon dioxide.
• As a base to synthesize cyclic carbonates using halo- or tosyl-alcohols and carbon dioxide in the absence of any transition metal or organo catalyst.
• In combination with alkyl halide and acetonitrile, it forms an effective system for the alkylation method of phenols.

Promotes the efficient O-alkylation of alcohols to form mixed alkyl carbonates.

Safety Information

• pictograms: GHS08,GHS05
• signalword: Danger
• hcodes: H318,H361f,H373
• pcodes: P202 - P260 - P280 - P305 + P351 + P338 - P308 + P313 - P405
• Hazard Classifications: Eye Dam. 1 - Repr. 2 - STOT RE 2 Oral
• target_organs: Kidney,Adrenal gland,Testes
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves