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Ciprofloxacin-d8 hydrochloride hydrate

VETRANAL®, analytical standard

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Synonym(s):
1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-d8-1-yl-1,4-dihydro-quinoline-3-carboxylic acid hydrochloride hydrate
Empirical Formula (Hill Notation):
C17D8H10FN3O3 · HCl · xH2O
CAS Number:
Molecular Weight:
375.85 (anhydrous basis)
MDL number:
PubChem Substance ID:

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

mass shift

M+8

SMILES string

O.Cl.[2H]C1([2H])NC([2H])([2H])C([2H])([2H])N(c2cc3N(C=C(C(O)=O)C(=O)c3cc2F)C4CC4)C1([2H])[2H]

InChI

1S/C17H18FN3O3.ClH.H2O/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;;/h7-10,19H,1-6H2,(H,23,24);1H;1H2/i3D2,4D2,5D2,6D2;;

InChI key

ARPUHYJMCVWYCZ-CORRJWLCSA-N

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This Item
PHR11673343432983
Ciprofloxacin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1167

Ciprofloxacin

Ciprofloxacin VETRANAL®, analytical standard

Supelco

33434

Ciprofloxacin

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

application(s)

pharmaceutical (small molecule)

application(s)

agriculture
environmental
forensics and toxicology
pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

neat

Quality Level

100

Quality Level

300

Quality Level

100

Quality Level

100

General description

Ciprofloxacins are classified under the fluoroquinolones group of antibiotics.

Application

Ciprofloxacin-d8 hydrochloride hydrate may be used to prepare ciprofloxacin-d8 that can be used as an internal standard for the determination of ciprofloxacin in:
  • Groundwater samples collected from cemetery areas, urban wastewater samples and dairy products by ultra-high performance liquid chromatography-triple quadrupole mass spectrometry (UHPLC-MS/MS) equipped with electrospray ionization (ESI) source and multiple reaction monitoring (MRM) mode of detection.
  • Hospital wastewater and chicken feces by LC-MS/MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Sub-and super-critical water oxidation of wastewater containing amoxicillin and ciprofloxacin.
Stavbar S, et al.
Journal of Supercritical Fluids, 128(3), 73-78 (2017)
Determination of pharmaceuticals in groundwater collected in five cemeteries' areas (Portugal).
Paiga P and Delerue-Matos C
The Science of the Total Environment, 569(3), 16-22 (2016)
Analysis of multiclass antibiotic residues in urban wastewater in Tunisia.
Harrabi M, et al.
Environmental Nanotechnology, Monitoring & Management, 10(3), 163-170 (2018)
Development and Validation of a Multi-class UHPLC-MS/MS Method for Determination of Antibiotic Residues in Dairy Products.
Schwaiger B, et al.
Food Analytical Methods, 10(3), 1-18 (2018)
Pilar Gómez-Ramírez et al.
International journal of environmental research and public health, 17(11) (2020-06-11)
Pharmaceuticals are still considered emerging pollutants affecting both aquatic and terrestrial ecosystems. Scavenging bird species may be exposed to veterinary drugs when they feed on livestock carcasses provided at supplementary feeding stations, as these are often stocked with ailing and/or

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