Recommended Products
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
storage temp.
−20°C
SMILES string
CN[C@@H]1C[C@@H]2O[C@@](C)([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35
InChI
1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20?,26-,28+/m1/s1
InChI key
HKSZLNNOFSGOKW-ZGQXJOJZSA-N
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General description
Application
- Protein Painting for Structural Analysis: This research utilizes staurosporine′s role in protein kinase inhibition to develop a technique called protein painting, which is essential for structural and binding site analysis. This approach enhances understanding of protein interactions and can be pivotal in drug design, particularly in targeting specific kinase enzymes in cancer research (Zheng Z et al., 2024).
- Identification of Anthelmintic Activities: Staurosporine is employed to identify small molecule inhibitors that target conserved proteins among gastrointestinal nematodes. This study not only highlights its role in parasitic infection treatments but also its broader applications in developing antiparasitic drugs, leveraging its properties as a potent kinase inhibitor (Jung H et al., 2024).
- Development of Novel Cytoprotective Compounds: Focusing on mitochondria-dependent cell death, this research explores staurosporines potential to inhibit pathways involved in cellular apoptosis. This is particularly crucial in developing therapeutic strategies against diseases characterized by unwanted cell death, such as neurodegenerative diseases and certain types of cancer (Matsuyama M et al., 2023).
Other Notes
Legal Information
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 4 - Repr. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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