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Sigma-Aldrich

Potassium antimonyl tartrate trihydrate

ACS reagent, ≥99%

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Synonym(s):
Antimony potassium tartrate trihydrate, Tartar emetic
Empirical Formula (Hill Notation):
C8H4K2O12Sb2 · 3H2O
CAS Number:
Molecular Weight:
667.87
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent

Quality Level

Assay

≥99%
99.0-103.0%

form

powder

impurities

≤0.020 meq/g Titr. acid or base

loss

≤2.7% loss on drying

mp

≥300 °C (lit.)

solubility

water: soluble

cation traces

As: ≤0.015%

SMILES string

O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O

InChI

1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4

InChI key

WBTCZEPSIIFINA-UHFFFAOYSA-J

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This Item
6006311126230057
assay

≥99%, 99.0-103.0%

assay

99.0-103% (RT)

assay

99.0-103.0%

assay

99.95% trace metals basis

form

powder

form

-

form

powder

form

powder

impurities

≤0.020 meq/g Titr. acid or base

impurities

-

impurities

≤0.02 mmol/g free acid, ≤0.02 mmol/g free alkali

impurities

≤550.0 ppm Trace Metal Analysis

mp

≥300 °C (lit.)

mp

≥300 °C (lit.)

mp

≥300 °C (lit.)

mp

-

solubility

water: soluble

solubility

-

solubility

-

solubility

-

General description

Potassium antimonyl tartrate trihydrate is a metalloid salt in which the antimony is in trivalent state (SbIII). Potassium antimonyl tartrate (PAT) is an antiparasitic agent predominantly used for treating infections caused by the parasite Leishmania. Its antiangiogenic and antitumor properties has been investigated in nonsmall-cell lung cancer (NSCLC) cells. Studies in Chinese hamster ovary cells show that it may prevent the repair of DNA double strand breaks (DSBs) caused by γ-irradiation.

Application

Potassium antimonyl tartrate trihydrate has been used in the dose-inhibition experiments to evaluate the dose-inhibition curves of antimony-based antileishmanial compounds against Leishmania promastigotes in medium 199.
Potassium antimonyl tartrate trihydrate may be used to prepare antimony (Sb(III)) stock solution in deionized water (100mg/L). It may also be employed in the spectrophotometric determination of total phosphorus in dry sediments.

Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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