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Supelco

Mettler-Toledo Calibration substance ME 51143091, Saccharin

traceable to primary standards (LGC)

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Synonym(s):
Saccharin, 2,3-Dihydroxy-1,2-benzisothiazol-3-one-1,1-dioxide, 2-Sulfobenzoic acid imide, o-Benzoic sulfimide
Empirical Formula (Hill Notation):
C7H5NO3S
CAS Number:
Molecular Weight:
183.18
Beilstein:
6888
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

quality

traceable to primary standards (LGC)

shelf life

limited shelf life, expiry date on the label

mp

226-229 °C (lit.)

application(s)

food and beverages
pharmaceutical

format

neat

SMILES string

O=C1NS(=O)(=O)c2ccccc12

InChI

1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)

InChI key

CVHZOJJKTDOEJC-UHFFFAOYSA-N

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1 of 4

This Item
PHR13412409311607007
Saccharin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1341

Saccharin

Saccharin ≥99%

Sigma-Aldrich

240931

Saccharin

Saccharin United States Pharmacopeia (USP) Reference Standard

USP

1607007

Saccharin

mp

226-229 °C (lit.)

mp

226-229 °C (lit.)

mp

226-229 °C (lit.)

mp

226-229 °C (lit.)

application(s)

food and beverages
pharmaceutical

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

-

format

neat

quality

traceable to primary standards (LGC)

quality

-

quality

-

quality

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

General description

Mettler-Toledo calibration substance ME 51143091, saccharin is an analytical standard, designed for the routine calibration of Mettler-Toledo melting point instrument. Its value is an average of 6 to 12 measurements with a Mettler-Toledo MP90 Excellence instrument that is calibrated against primary standards. The melting point is validated by Capillary method as per European Pharmacopeia (2.2.14.)

Application

Saccharin Mettler-Toledo calibration substance ME 51143091 is a melting point calibration standard used to calibrate Mettler-Toledo mp instruments.

Biochem/physiol Actions

A sweet tastant for mammals. A glycerol taste receptor binding site specific for glucose has been proposed in drosophila.

Features and Benefits

  • Traceable to a primary standard from LGC, London
  • Melting point evaluation conducted in both thermodynamic and pharmacopeia modes for physically correct and heating rate dependent melting point determinations, respectively
  • Available with certificates of analysis and safety data sheet
  • A product of analytical standard grade to help meet the QC/QA requirements of melting point determination
  • Uncertainty of measurement up to ± 0.3 °C

Legal Information

Mettler-Toledo is a registered trademark of Mettler-Toledo, Inc.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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A process for the regioselective amination of unsymmetrical 3,5-substituted pyridine N-oxides has been developed utilizing cheap, readily available saccharin as an ammonium surrogate. High conversions of the corresponding saccharin adducts have been achieved under mild reaction conditions. In situ deprotection
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