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42754

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Ginsenoside Rk1

analytical standard

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Synonym(s):
(3β, 12β)-12-Hydroxydammara-20,24-dien-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
Empirical Formula (Hill Notation):
C42H70O12
CAS Number:
Molecular Weight:
767.00
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

format

neat

storage temp.

2-8°C

SMILES string

CC1(C)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)CC[C@@]4(C)[C@@]1([H])CC[C@]5(C)[C@]4([H])C[C@@H](O)[C@@]6([H])[C@@]5(C)CC[C@@]6(C(CCC=C(C)C)=C)[H]

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This Item
PHR220068317PHL89214
Ginsenoside Rk1 analytical standard

Supelco

42754

Ginsenoside Rk1

Ginsenoside Rg1 certified reference material, pharmaceutical secondary standard

Supelco

PHR2200

Ginsenoside Rg1

Ginsenoside Rg1 analytical standard

Supelco

68317

Ginsenoside Rg1

Ginsenoside Rg1 phyproof® Reference Substance

PHL89214

Ginsenoside Rg1

format

neat

format

neat

format

neat

format

-

assay

≥95.0% (HPLC)

assay

-

assay

≥90% (HPLC)

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

Quality Level

100

Quality Level

300

Quality Level

100

Quality Level

-

General description

Ginsenoside Rk1 is the major bioactive component isolated from heat-processed Panax ginseng Meyer (ginseng) plants. It is a monomeric compound that has been reported to exhibit anti-inflammatory, anti-allergic, and anti-tumor properties and is utilized for the treatment of cancer and diabetes mellitus.

Application

Ginsenoside Rk1 may be used as an analytical reference standard for the determination of the analyte in Panax ginseng preparations and Chinese medicine formula Sheng-Mai San (SMS) and rat plasma samples (post administration of SMS) by chromatography techniques.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis
Kim YJ, et al.
Biological & Pharmaceutical Bulletin, 31(5), 826-830 (2008)
Simultaneous determination of 30 ginsenosides in Panax ginseng preparations using ultra performance liquid chromatography
Park HW, et al.
Journal of ginseng research, 37(4), 457-457 (2013)
Ginsenoside Rk1 suppresses pro-inflammatory responses in lipopolysaccharide-stimulated RAW264. 7 cells by inhibiting the Jak2/Stat3 pathway
Qian YU, et al.
Chinese Journal of Natural Medicines, 15(10), 751-757 (2017)
Identification of multiple constituents in the traditional Chinese medicine formula Sheng-Mai San and rat plasma after oral administration by HPLC-DAD-MS/MS
Wang YH, etal.
Journal of Pharmaceutical and Biomedical Analysis, 54(5), 1110-1127 (2011)
Simultaneous quantification of 14 ginsenosides in Panax ginseng CA Meyer (Korean red ginseng) by HPLC-ELSD and its application to quality control.
Kim NS, et al.
Journal of Pharmaceutical and Biomedical Analysis, 45(1), 164-170 (2007)

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