439126

Acetone

suitable for HPLC, ≥99.9%

• Linear Formula: CH₃COCH₃
• CAS Number: 67-64-1
• Molecular Weight: 58.08
• Beilstein/REAXYS Number: 635680
• EC Number: 200-662-2
• MDL number: MFCD00008765
• UNSPSC Code: 12190000
• PubChem Substance ID: 57650186
• NACRES: NA.02
• grade: HPLC grade
• assay: ≥99.9%
• technique(s): HPLC: suitable
• bp: 56 °C/760 mmHg (lit.)
• vapor pressure: 184 mmHg ( 20 °C)

Properties

• grade: HPLC grade
• Quality Level: 100
• vapor density: 2 (vs air)
• vapor pressure: 184 mmHg ( 20 °C)
• assay: ≥99.9%
• form: liquid
• expl. lim.: 13.2 %
• technique(s): HPLC: suitable
• impurities: ≤0.5% (water)
• evapn. residue: <0.0002%

Description

General description

Acetone is a ketone. Mixtures of TiO₂ (P25) with rare earth oxides (La₂O₃ or Y₂O₃) calcined at 700°C or 650°C has been reported to efficiently photocatalyze the oxidation of acetone.[1] Its aldol condensation in vapor-phase has been investigated over MgO promoted with alkali (Li, Na, K and Cs) or alkaline earth (Ca, Sr and Ba) metal ions.[2] It undergoes Aldol condensation in the presence of Mg-Al layered double hydroxides (LDH) as catalysts and Cl^- and/or CO₃^2- as compensating anions to afford diacetone alcohol and mesityl oxide.[3] Enantioselective Aldol condensation of acetone with various isatins in the presence of dipeptides (catalyst) has been described.[4]

Application

Acetone was used in the affinity purification of modified proteins using streptavidin beads for the mass spectrometric (MS) identification of poly(ADP-ribose) polymerases (PARP) substrate proteins.[5]
It may be used in the following studies:

• NMR spectroscopic evaluation of glucose metabolism in biological samples (blood).[6]
• Preparation of 13wt% amorphous poly (lactic acid) (PLA) solution, which was required for the preparation of electrospun PLA membranes.[7]
• As a precursor for the synthesis of methyl isobutyl ketone (MIBK) in the presence of sulfonated graphene oxide-Pd/cordierite catalyst.[8]
• Synthesis of (4-hydroxymethyl-2,2-dimethyl-1,3-dioxolane), a solketal from glycerol using supercritical fluids (SCF) technology.[9]

It may be used in the synthesis of the following acetone hydrazones:

• 1-isopropylidene-2-methylhydrazine[10]
• 1-isopropylidene-2-hydroxyethylhydrazine[10]
• 1-isopropylidene-2-formylhydrazine[10]

Acetone′s luminesence intensity is dependent upon the solution components . The absorption of UV light by acetone, results in its photolysis and the production of radials .

Packaging

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Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H319,H336
• pcodes: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• target_organs: Central nervous system
• supp_hazards: EUH066
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 1.4 °F - closed cup
• flash_point_c: -17.0 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves