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51239

Millipore

Oxytetra Selective Supplement

suitable for microbiology

Synonym(s):

Oxytetracycline, OGYE Selective Supplement

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About This Item

Empirical Formula (Hill Notation):
C22H24N2O9
CAS Number:
Molecular Weight:
460.43
EC Number:
MDL number:
UNSPSC Code:
41171614
PubChem Substance ID:
NACRES:
NA.85

sterility

sterile

Quality Level

form

powder

shelf life

limited shelf life, expiry date on the label

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

application(s)

environmental
food and beverages
pharmaceutical

microbiology

mode of action

protein synthesis | interferes

suitability

molds
yeasts

SMILES string

CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O

InChI

1S/C22H24N2O9/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31)/t12-,13-,14+,17+,21-,22+/m1/s1

InChI key

IWVCMVBTMGNXQD-PXOLEDIWSA-N

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General description

Chemical structure: tetracycline

Application

Oxytetracycline is used as an antibacterial selective agent in microbiology studies . It is a broad spectrum antibiotic that is active against a wide variety of bacteria. When added to OGY-Agar (Cat. No. 75310) Oxytetracycline suppresses the growth of accompanying bacterial flora during culturing yeasts and molds.

Biochem/physiol Actions

Oxytetracycline is a protein synthesis inhibitor .

Features and Benefits

Added to OGY-Agar (Cat. No. 75310) or OGYE ChromoSelect Agar (Cat. No. 66481) Oxytetracycline suppresses the growth of accompanying bacterial flora during culturing yeasts and moulds.

Components

(per vial sufficient for 500 ml medium)
Oxytetracycline 50.0 mg

Related product

Product No.
Description
Pricing

pictograms

Health hazardEnvironment

signalword

Warning

Hazard Classifications

Aquatic Chronic 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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E M MIKOLAJCIK et al.
Applied microbiology, 11, 418-422 (1963-09-01)
Induction of oxytetracycline resistance in a strain of Streptococcus lactis caused this organism to display reduced acid production, salt tolerance, pyruvate synthesis, growth at alkaline pH, and a loss in ability to produce ammonia from arginine. alpha-Ketoglutaric and oxaloacetic acids
P R Spooner
Parasitology, 101 Pt 3, 387-393 (1990-12-01)
Oxytetracycline (OTC) significantly inhibited cytochrome c oxidase activity in bovine lymphocytes infected with Theileria parva and in uninfected mitogen-stimulated lymphocytes. The inhibitory effect was detected in vitro within 24 h of treatment with drug concentrations as low as 1 micrograms/ml.
Pavel Novy et al.
The Journal of antimicrobial chemotherapy, 66(6), 1298-1300 (2011-03-23)
In this study we examined the in vitro synergistic effect of baicalin, the flavone constituent of Scutellaria spp., in combinations with oxytetracycline and tetracycline on the growth of Staphylococcus aureus. The MICs were determined by the broth microdilution method and
Getu Kahsay et al.
Journal of pharmaceutical and biomedical analysis, 75, 199-206 (2013-01-02)
A simple, robust and fast high-performance liquid chromatographic method is described for the analysis of oxytetracycline and its related impurities. The principal peak and impurities are all baseline separated in 20 min using an Inertsil C₈ (150 mm × 4.6
A L Stanton et al.
Journal of dairy science, 95(9), 4950-4960 (2012-08-25)
Bovine respiratory disease complex (BRD) is a common disease in weaned dairy calves that incurs economic and welfare costs. This study was an extension of a randomized clinical trial in which a single injection of tulathromycin (TUL) or oxytetracycline (TET)

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