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52517

Supelco

1,1,1,3,3,3-Hexafluoro-2-propanol

for GC derivatization, LiChropur, ≥99.8%

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Synonym(s):
HFP, Hexafluoroisopropanol
Linear Formula:
(CF3)2CHOH
CAS Number:
Molecular Weight:
168.04
Beilstein/REAXYS Number:
1841007
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.05

grade

for GC derivatization

Quality Level

assay

≥99.8% (GC)
≥99.8%

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations

reagent type: derivatization reagent
reaction type: Esterifications

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.275 (lit.)

bp

59 °C (lit.)

mp

−4 °C (lit.)

density

1.596 g/mL at 25 °C (lit.)

SMILES string

OC(C(F)(F)F)C(F)(F)F

InChI

1S/C3H2F6O/c4-2(5,6)1(10)3(7,8)9/h1,10H

InChI key

BYEAHWXPCBROCE-UHFFFAOYSA-N

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1 of 4

This Item
105228PHR334918127
vibrant-m

52517

1,1,1,3,3,3-Hexafluoro-2-propanol

vibrant-m

105228

1,1,1,3,3,3-Hexafluoro-2-propanol

vibrant-m

PHR3349

Sevoflurane Related Compound C

vibrant-m

18127

1,1,1,3,3,3-Hexafluoro-2-propanol

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations, reagent type: derivatization reagent
reaction type: Esterifications

reaction suitability

-

reaction suitability

-

reaction suitability

-

assay

≥99.8% (GC)

assay

≥99%

assay

-

assay

≥99.8% (GC)

bp

59 °C (lit.)

bp

59 °C (lit.)

bp

59 °C (lit.)

bp

59 °C (lit.)

density

1.596 g/mL at 25 °C (lit.)

density

1.596 g/mL at 25 °C (lit.)

density

1.596 g/mL at 25 °C (lit.)

density

1.596 g/mL at 25 °C (lit.)

mp

−4 °C (lit.)

mp

−4 °C (lit.)

mp

−4 °C (lit.)

mp

−4 °C (lit.)

General description

Hexafluoroisopropanol (HFP) is generally used to denature the native state of proteins, and it also stabilizes the a-helical conformation in unfolded peptides and proteins like ß-lactoglobulin and melittin.

Application

Suitable for the derivatization of glutamic acid, homovanillic, iso-homovanillic and dihydroxyphenyl acetic acids and Υ-aminobutyric acid.

Other Notes

Reagent for hexafluoroisopropyl ester, N-pentafluoropropionyl, and trifluoroacetyl..
Size-exclusion chromatography in 1,1,1,3,3,3-hexafluoro-2-propanol

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

CorrosionHealth hazard

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Repr. 2 - Skin Corr. 1A - STOT RE 2

Storage Class

8A - Combustible, corrosive hazardous materials

wgk_germany

WGK 2

flash_point_f

No data available

flash_point_c

No data available

ppe

Faceshields, Gloves, Goggles


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