685461

Acetonitrile solution

suitable for HPLC, contains 10.0% acetone, 40.0% 2-propanol, 0.05% formic acid

• Synonym(s): ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide
• Linear Formula: CH₃CN
• CAS Number: 75-05-8
• Molecular Weight: 41.05
• Beilstein/REAXYS Number: 4124158
• MDL number: MFCD00001878
• UNSPSC Code: 12190000
• PubChem Substance ID: 329760972

Properties

• product name: Acetonitrile solution, contains 10.0% acetone, 0.05% formic acid, 40.0% 2-propanol
• vapor density: 1.41 (vs air)
• Quality Level: 100
• vapor pressure: 72.8 mmHg
• form: liquid
• contains: 0.05% formic acid; 10.0% acetone; 40.0% 2-propanol
• expl. lim.: 8 %
• technique(s): HPLC: suitable
• bp: 81-82 °C
• mp: -48 °C
• density: 0.782 g/mL at 25 °C
• application(s): food and beverages
• format: mixture
• SMILES string: CC#N
• InChI: 1S/C2H3N/c1-2-3/h1H3
• InChI key: WEVYAHXRMPXWCK-UHFFFAOYSA-N

Description

General description

The product is an acetonitrile solution containing 40.0% 2-propanol, 0.05% formic acid, 10.0% acetone. This pre-blended solvent is of high purity that reduces time-consuming preparation and prevents instrument downtime because of impure mobile phases. Acetonitrile (MeCN), an organic solvent has low viscosity, high elution strength and is UV transparent at low wavelength.

Application

• Preparation and characterization of stationary phase gradients on C8 liquid chromatography columns.: This research discusses the preparation of stationary phase gradients on C8 columns using acetonitrile solutions, enhancing chromatographic resolution and efficiency, pivotal for the analytical chemistry field (Cecil et al., 2024).


• Metal-cation-induced shifts in thiolate redox and reduced sulfur speciation.: Highlighting a study on the redox behavior of thiolates influenced by metal cations, where acetonitrile solutions were crucial for maintaining reaction environments, crucial for developing new catalytic and sensor applications (Seo et al., 2024).


• A Phosphine-Oxide Cobalt(II) Complex and Its Catalytic Activity Studies toward Alcohol Dehydrogenation Triggered Direct Synthesis of Imines and Quinolines.: This paper presents the synthesis of a novel cobalt(II) complex using acetonitrile solution, which showed significant catalytic activity in synthesizing bioactive molecules, illustrating the solvent′s role in facilitating complex chemical reactions (Khatua et al., 2024).


• [Simultaneous determination of 31 banned veterinary drugs during egg-laying period in poultry eggs by ultra performance liquid chromatography-tandem mass spectrometry].: Demonstrating the use of acetonitrile solutions in sample preparation for high-throughput UPLC-MS/MS analysis, this study significantly contributes to food safety and drug residue analysis (Zhu et al., 2024).


• Probing Isolated Water Molecules in Aqueous Acetonitrile Solutions Using Oxygen K-Edge X-ray Absorption Spectroscopy.: This research utilizes acetonitrile solutions to study the interaction of water molecules at the molecular level, providing insights critical for understanding solvation dynamics and mixture behaviors (Nagasaka, 2024).

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H302,H319,H336
• pcodes: P210 - P233 - P240 - P241 - P301 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 14.0 - 23.0 °F - closed cup
• flash_point_c: -10 - -5 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter