74147

Iohexol

analytical standard

• Synonym(s): 5-[N-(2,3-Dihydroxypropyl)acetamido]-2,4,6-triiodo-N,N′-bis(2,3-dihydroxypropyl)isophthalamide
• Empirical Formula (Hill Notation): C₁₉H₂₆I₃N₃O₉
• CAS Number: 66108-95-0
• Molecular Weight: 821.14
• Beilstein/REAXYS Number: 2406632
• EC Number: 266-164-2
• MDL number: MFCD00077732
• UNSPSC Code: 41116107
• PubChem Substance ID: 329765500
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• assay: ≥95.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• impurities: ≤6.0% water
• application(s): clinical testing
• format: neat
• SMILES string: IC1=C(C(NCC(O)CO)=O)C(I)=C(C(NCC(CO)O)=O)C(I)=C1N(CC(CO)O)C(C)=O
• InChI: 1S/C19H26I3N3O9/c1-8(29)25(4-11(32)7-28)17-15(21)12(18(33)23-2-9(30)5-26)14(20)13(16(17)22)19(34)24-3-10(31)6-27/h9-11,26-28,30-32H,2-7H2,1H3,(H,23,33)(H,24,34)
• InChI key: NTHXOOBQLCIOLC-UHFFFAOYSA-N

Description

General description

Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker to determine the glomerular filtration rate (GFR) which measures the level of kidney function. It finds applications in angiographic and urography procedures.

Application

Iohexol may be used as an internal standard for the determination of iohexol in human plasma, serum and urine samples by HPLC-UV method. It may also be used as a model compound to analyze the applicability of iohexol for glomerular filtration rate (GFR) measurement by the plasma clearance of iohexol in investigating renal failure.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety Information

• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable