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81210

Sigma-Aldrich

Poly(ethylene glycol)

average Mw 1,500

Synonym(s):
PEG
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

form

solid

Quality Level

mol wt

average Mw 1,500

mp

45-50 °C

transition temp

Tm 45-50 °C

Ω-end

hydroxyl

α-end

hydroxyl

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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This Item
812538125581189
Poly(ethylene glycol) average Mw 1,500

Sigma-Aldrich

81210

Poly(ethylene glycol)

Poly(ethylene glycol) BioUltra, for molecular biology, 6,000

Sigma-Aldrich

81253

Poly(ethylene glycol)

Poly(ethylene glycol) BioUltra, 6,000

Sigma-Aldrich

81255

Poly(ethylene glycol)

Poly(ethylene glycol) BioUltra, for molecular biology, 1,000

Sigma-Aldrich

81189

Poly(ethylene glycol)

mol wt

average Mw 1,500

mol wt

Mr 5000-7000

mol wt

Mr 5000-7000

mol wt

Mr 950-1050

mp

45-50 °C

mp

-

mp

-

mp

-

transition temp

Tm 45-50 °C

transition temp

-

transition temp

-

transition temp

-

Ω-end

hydroxyl

Ω-end

-

Ω-end

-

Ω-end

-

α-end

hydroxyl

α-end

-

α-end

-

α-end

-

General description

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, required for the purification of biological materials. PEG also interacts with cell membrane, thereby resulting in cell fusion.

Application

Poly(ethylene glycol) has been used for histological, histochemical and immunohistochemical evaluation of in vitro cultured beads. It has been used for the fusion of cells.

Other Notes

Molecular weight range: 1,400-1,600

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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705578-5MG-PW

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MMYOMAG-74K-13

1000309185

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Chondrogenesis of human mesenchymal stem cells encapsulated in alginate beads.
Ma HL et al.
Journal of Biomedical Materials Research Part A, 64, 273-273 (2003)
DC-SIGN (CD209) expression is IL-4 dependent and is negatively regulated by IFN, TGF-beta, and anti-inflammatory agents.
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Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives.
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The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene

Articles

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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