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92688

Supelco

5,5-Dimethyl-1-pyrroline N-oxide

for ESR-spectroscopy

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Synonym(s):
DMPO
Empirical Formula (Hill Notation):
C6H11NO
CAS Number:
Molecular Weight:
113.16
Beilstein/REAXYS Number:
107603
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

grade

for ESR-spectroscopy

Quality Level

assay

≥98.0% (GC)

form

crystals

refractive index

n20/D 1.496 (lit.)

bp

75 °C/0.4 mmHg (lit.)

mp

25-29 °C (lit.)

density

1.015 g/mL at 25 °C (lit.)

storage temp.

−20°C

SMILES string

CC1(C)CCC=[N+]1[O-]

InChI

1S/C6H11NO/c1-6(2)4-3-5-7(6)8/h5H,3-4H2,1-2H3

InChI key

VCUVETGKTILCLC-UHFFFAOYSA-N

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1 of 4

This Item
41661MX1458P1037
5,5-Dimethyl-1-pyrroline N-oxide for ESR-spectroscopy

92688

5,5-Dimethyl-1-pyrroline N-oxide

Dimethyl sulfoxide Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs GR ACS

MX1458

Dimethyl sulfoxide

Phenol for molecular biology

P1037

Phenol

assay

≥98.0% (GC)

assay

≥99.0% (GC)

assay

≥99.9% (GC)

assay

≥99.0% (GC)

Quality Level

100

Quality Level

-

Quality Level

200

Quality Level

100

storage temp.

−20°C

storage temp.

-

storage temp.

room temp

storage temp.

2-8°C

grade

for ESR-spectroscopy

grade

-

grade

-

grade

for molecular biology

refractive index

n20/D 1.496 (lit.)

refractive index

n20/D 1.488 (lit.), n20/D 1.489

refractive index

n20/D 1.479 (lit.)

refractive index

-

Application

5,5-Dimethyl-1-pyrroline N-oxide is a reagent generally used either as a free-radical spin-trapping agent, or electrophilic component during the synthesis of pyrrolidine derivatives. It may also be considered as 1,3-dipole in cycloaddition processes.
Neuroprotective agent; nitric oxide spin trap. Used to study radicals formed by enzymatic acetaldehyde oxidation. Incubation of lymphocytes with DMPO decreased DNA damage by NiCl2.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

203.0 °F - closed cup

flash_point_c

95 °C - closed cup


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Suchandra Bhattacharjee et al.
Nucleic acids research, 40(12), 5477-5486 (2012-03-06)
Oxidative stress-related damage to the DNA macromolecule produces lesions that are implicated in various diseases. To understand damage to DNA, it is important to study the free radical reactions causing the damage. Measurement of DNA damage has been a matter
Emiko Sato et al.
Journal of biochemistry, 150(2), 173-181 (2011-05-17)
The nicotinamide adenine dinucleotide (NADH)/nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and the xanthine oxidase (XOD) systems generate reactive oxygen species (ROS). In the present study, to characterize the difference between the two systems, the kinetics of ROS generated by both
Pedro L Zamora et al.
The journal of physical chemistry. A, 116(26), 7210-7218 (2012-06-07)
Radical forms of sulfur dioxide (SO(2)), sulfite (SO(3)(2-)), sulfate (SO(4)(2-)), and their conjugate acids are known to be generated in vivo through various chemical and biochemical pathways. Oxides of sulfur are environmentally pervasive compounds and are associated with a number
Ronald P Mason
Free radical biology & medicine, 36(10), 1214-1223 (2004-04-28)
The detection of protein free radicals using the specific free radical reactivity of nitrone spin traps in conjunction with nitrone-antibody sensitivity and specificity greatly expands the utility of the spin trapping technique, which is no longer dependent on the quantum
Patrick T Kang et al.
Free radical biology & medicine, 53(4), 962-973 (2012-05-29)
Complex I is a critical site of O(2)(•-) production and the major host of reactive protein thiols in mitochondria. In response to oxidative stress, complex I protein thiols at the 51- and 75-kDa subunits are reversibly S-glutathionylated. The mechanism of

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