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A7222

Sigma-Aldrich

8-Aminopyrene-1,3,6-trisulfonic acid trisodium salt

≥96.0% (HPCE), solid

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Synonym(s):
1,3,6-Pyrenetrisulfonic acid, 8-amino trisodium salt, APTS, Trisodium 8-aminopyrene-1,3,6-trisulfonate
Empirical Formula (Hill Notation):
C16H8NNa3O9S3
CAS Number:
Molecular Weight:
523.40
MDL number:
PubChem Substance ID:

Quality Level

assay

≥96.0% (HPCE)

form

solid

mp

≥250 °C (lit.)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

[Na+].[Na+].[Na+].Nc1cc(c2ccc3c(cc(c4ccc1c2c34)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/C16H11NO9S3.3Na/c17-11-5-12(27(18,19)20)8-3-4-10-14(29(24,25)26)6-13(28(21,22)23)9-2-1-7(11)15(8)16(9)10;;;/h1-6H,17H2,(H,18,19,20)(H,21,22,23)(H,24,25,26);;;/q;3*+1/p-3

InChI key

XSTNYACEWLNWPY-UHFFFAOYSA-K

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This Item
H1529230901D8284
application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

assay

≥96.0% (HPCE)

assay

≥96%

assay

97%

assay

≥98% (HPLC)

storage temp.

2-8°C

storage temp.

-

storage temp.

room temp

storage temp.

2-8°C

mp

≥250 °C (lit.)

mp

>300 °C (lit.)

mp

-

mp

-

Application

APTS is a fluorescence reagent that has been demonstrated to have a high level of detection sensitivity for sugars The LOD for APTS-derivatized sugars has been shown to be 0.4 nM when using a 488 nm argon-ion laser. The multi-anionic nature of APTS makes it ideal for the studies of carbohydrate molecules and small hormone molecules by high resolution capillary electrophoresis.
8-Aminopyrene-1,3,6-trisulfonic acid trisodium salt (APTS) has been used for the detection of human milk oligosaccharides using multiplexed CGE with LIF (capillary gel electrophoresis with laser-induced fluorescence) technique.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Development of a high-throughput glycoanalysis method for the characterization of oligosaccharides in human milk utilizing multiplexed capillary gel electrophoresis with laser-induced fluorescence detection.
Kottler R, et al.
Electrophoresis, 34, 2323-2336 (2013)
N N Xu et al.
Animal : an international journal of animal bioscience, 1-7 (2018-12-12)
Starchy grain is usually supplemented to diets containing low-quality forage to provide sufficient energy for ruminant animals. Ruminal degradation of grain starch mainly depends on the hydrolysis of the endosperm, which may be variable among grain sources. This study was
Alexandre Kreiss et al.
PloS one, 6(7), e22402-e22402 (2011-08-04)
Tasmanian devils (Sarcophilus harrisii) are on the verge of extinction due to a transmissible cancer, devil facial tumour disease (DFTD). This tumour is an allograft that is transmitted between individuals without immune recognition of the tumour cells. The mechanism to
Michael S Gilmore et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(23), 7273-7278 (2015-06-04)
Multidrug-resistant Enterococcus faecalis possess numerous mobile elements that encode virulence and antibiotic resistance traits as well as new metabolic pathways, often constituting over one-quarter of the genome. It was of interest to determine how this large accretion of mobile elements
Jie Chen et al.
PloS one, 10(6), e0127022-e0127022 (2015-06-16)
The aim of this study was to evaluate the diagnostic and differential diagnostic power of serum N-glycans for light chain multiple myeloma (LCMM). A total of 167 cases of subjects, including 42 LCMM, 42 IgG myeloma, 41 IgA myeloma, and

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