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BCR096

Dibenzo[a,l]pyrene

BCR®, certified reference material

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About This Item

Empirical Formula (Hill Notation):
C24H14
CAS Number:
191-30-0
Molecular Weight:
302.37
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329774220
MDL number:
MFCD00467035
Beilstein/REAXYS Number:
2054068

Key Documents

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Product Name

Dibenzo[a,l]pyrene, BCR®, certified reference material

InChI

1S/C24H14/c1-2-8-18-16(6-1)14-17-13-12-15-7-5-11-20-19-9-3-4-10-21(19)24(18)23(17)22(15)20/h1-14H

SMILES string

c1ccc2c(c1)cc3ccc4cccc5c6ccccc6c2c3c45

InChI key

JNTHRSHGARDABO-UHFFFAOYSA-N

grade

certified reference material

agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

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Analysis Note

For more information please see:
BCR096

Legal Information

BCR is a registered trademark of European Commission

pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

Hazard Classifications

Carc. 1B - Eye Dam. 1 - Muta. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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David M DeMarini et al.
Mutation research, 714(1-2), 17-25 (2011-06-22)
Benzo[a]pyrene (BP) and dibenzo[a,l]pyrene (DBP) are two polycyclic aromatic hydrocarbons (PAHs) that exhibit distinctly different mutagenicity and carcinogenicity profiles. Although some studies show that these PAHs produce unstable DNA adducts, conflicting data and arguments have been presented regarding the relative
Joseph B Guttenplan et al.
International journal of cancer, 130(12), 2783-2790 (2011-08-05)
Cancer of the oral cavity is a serious disease, affecting about 30,000 individuals in US annually. There are several animal models of oral cancer, but each has certain disadvantages. As a new model, we investigated whether topical application of the
David E Williams
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 155(1), 121-127 (2011-06-28)
Rainbow trout (Oncorhynchus mykiss) are an outstanding model of liver cancer induction by environmental chemicals and development of strategies for chemoprevention. Trout have critical and unique advantages allowing for cancer studies with 40,000 animals to determine dose-response at levels orders
David J Castro et al.
Cancer prevention research (Philadelphia, Pa.), 1(2), 128-134 (2009-01-14)
Dibenzo(a,l)pyrene (DBP) is among the most potent carcinogenic polycyclic aromatic hydrocarbons. Previously, we showed that DBP administration to pregnant mice resulted in high mortality of offspring from an aggressive T-cell lymphoma. All mice that survive to 10 months of age
Lyndsey E Shorey et al.
Toxicology and applied pharmacology, 270(1), 60-69 (2013-04-10)
Cruciferous vegetable components have been documented to exhibit anticancer properties. Targets of action span multiple mechanisms deregulated during cancer progression, ranging from altered carcinogen metabolism to the restoration of epigenetic machinery. Furthermore, the developing fetus is highly susceptible to changes
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Efficient PAH Analysis (EU 15+1) using an Ascentis® Express PAH HPLC Column

This application note describes the fast and efficient separation of the EU’s list of 15 + 1 polynuclear aromatic hydrocarbons (PAHs) using Ascentis® Express PAH HPLC column.

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