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Key Documents

F0060000

Fenticonazole nitrate

European Pharmacopoeia (EP) Reference Standard

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About This Item

Empirical Formula (Hill Notation):
C24H21Cl2N3O4S
CAS Number:
73151-29-8
Molecular Weight:
518.41
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

fenticonazole

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C24H20Cl2N2OS.HNO3/c25-19-8-11-22(23(26)14-19)24(15-28-13-12-27-17-28)29-16-18-6-9-21(10-7-18)30-20-4-2-1-3-5-20;2-1(3)4/h1-14,17,24H,15-16H2;(H,2,3,4)

InChI key

FJNRUWDGCVDXLU-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Fenticonazole nitrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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St Kovachev et al.
Akusherstvo i ginekologiia, 48(6), 18-23 (2009-01-01)
The aim of this study is to investigate the effectiveness of single-day treatment with oral fluconazole and topical fenticonazole in acute vulvovaginal candidosis (VVC). Infection was proven by detection of yeast cells and pseudohyphae on microscopic examination of vaginal wet
W Speed et al.
Rapid communications in mass spectrometry : RCM, 9(14), 1452-1456 (1995-01-01)
A method is described for the determination of fenticonazole in human female plasma. The method utilizes high performance liquid chromatography coupled to atmospheric pressure positive-ion chemical ionization triple quadrupole mass spectrometry. Multiple reaction monitoring is employed for selectivity and sensitivity
Srpski arhiv za celokupno lekarstvo, 140(7-8), 469-474 (2012-10-25)
Uncomplicated vulvovaginal candidiasis appears in 75% women of reproductive age. The most frequent causes are Candida albicans (85-95%) or C. glabrata, and infrequently C. krusei, C. tropicalis, C. parapsilosis, C. pseudotropicalis, etc. The aim of the study was to investigate
F Murina et al.
Minerva ginecologica, 64(2), 89-94 (2012-04-07)
The aim of this paper was to compare the efficacy of fluconazole 150 mg and intra-vaginal fenticonazole 600mg in short-course treatment of the acute episode of vulvovaginal candidiasis (VVC). In a prospective study, 80 patients with clinical and mycological (SavvyCheck™
A G Lawrence et al.
Current medical research and opinion, 12(2), 114-120 (1990-01-01)
An open, randomized comparative clinical trial was performed in 153 patients suffering from symptomatic vaginal candidiasis confirmed by mycological tests. Patients were allocated at random into two groups: the first group (consisting of 75 subjects) was treated with a single
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