M8304

Malic acid

meets USP/NF testing specifications

• Synonym(s): DL-Malic acid, (±)-2-Hydroxysuccinic acid, DL-Hydroxybutanedioic acid
• Linear Formula: HO₂CCH₂CH(OH)CO₂H
• CAS Number: 6915-15-7
• Molecular Weight: 134.09
• Beilstein/REAXYS Number: 1723539
• EC Number: 230-022-8
• MDL number: MFCD00064212
• UNSPSC Code: 12352100
• PubChem Substance ID: 24897242
• NACRES: NA.21

Properties

• agency: meets USP/NF testing specifications
• Quality Level: 200
• vapor density: 4.6 (vs air)
• vapor pressure: <0.1 mmHg ( 20 °C)
• form: solid
• autoignition temp.: 644 °F
• mp: 131-133 °C (lit.)
• application(s): pharmaceutical (small molecule)
• functional group: carboxylic acid; hydroxyl
• SMILES string: OC(CC(O)=O)C(O)=O
• InChI: 1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)
• InChI key: BJEPYKJPYRNKOW-UHFFFAOYSA-N

Description

General description

Malic acid is a dicarboxylic acid that can be prepared by hydration of maleic acid or fumaric acid. Its ability to prevent the oxidative degradation of lipids has been assessed. The impact of malic acid in the alteration of calcium chloride crystal morphology has been studied. The dissolution kinetics of kaolinite in malic acid have been reported. This product is a high quality pharmacopoeia product that meets the testing specifications of USP (United States Pharmacopoeia). It can be employed in research and pilot studies.

Application

• Microbiome-metabolomics analysis reveals abatement effects of itaconic acid on odorous compound production in Arbor Acre broilers.: This study explores the role of itaconic acid in reducing odorous compounds in poultry through microbiome and metabolomics analysis (Zhu et al., 2023).


• Influence of Carbon Sources on the Phenolic Compound Production by Euglena gracilis Using an Untargeted Metabolomic Approach.: The research investigates the impact of various carbon sources on phenolic compound production in Euglena gracilis through metabolomics (Bernard and Guéguen, 2022).


• Polymalic acid for translational nanomedicine.: This review highlights the biomedical applications of polymalic acid, focusing on its role in nanomedicine and sustainable production methods (Huang et al., 2022).


• Integrated Proteomics and Metabolomics Analysis of Nitrogen System Regulation on Soybean Plant Nodulation and Nitrogen Fixation.: The study examines the regulatory effects of nitrogen on soybean nodulation and nitrogen fixation using proteomics and metabolomics techniques (Lyu et al., 2022).


• Sustainable production and biomedical application of polymalic acid from renewable biomass and food processing wastes.: This paper discusses the sustainable production of polymalic acid from biomass and its biomedical applications (Zou et al., 2021).

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: 397.4 °F
• flash_point_c: 203 °C
• ppe: dust mask type N95 (US), Eyeshields, Gloves