N0250000

Naproxen

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid
• Linear Formula: CH₃OC₁₀H₆CH(CH₃)CO₂H
• CAS Number: 22204-53-1
• Molecular Weight: 230.26
• Beilstein/REAXYS Number: 3591068
• MDL number: MFCD00010500
• UNSPSC Code: 41116107
• PubChem Substance ID: 329818408
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: naproxen
• manufacturer/tradename: EDQM
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 152-154 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
• InChI: 1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
• InChI key: CMWTZPSULFXXJA-VIFPVBQESA-N
• Gene Information: human ... PTGS1(5742) , PTGS2(5743)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Naproxen EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Non-selective cyclooxygenase (COX-1 and COX-2) inhibitor.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS08,GHS07,GHS09
• signalword: Warning
• hcodes: H302,H315,H319,H335,H361fd,H411
• pcodes: P202 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3