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PHR1367

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Sorbic acid

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
Sorbic acid, α-trans-γ-trans-Sorbic acid, (E,E)-1,3-Pentadiene-1-carboxylic acid, 2,4-Hexadienoic acid, 2E,4E-Hexadienoic acid, trans,trans-2,4-Hexadienoic acid, C6:2n-2,4, NSC 35405, NSC 49103, NSC 50268
Linear Formula:
CH3CH=CHCH=CHCOOH
CAS Number:
Molecular Weight:
112.13
Beilstein/REAXYS Number:
1098547
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to USP 1615956

vapor pressure

0.01 mmHg ( 20 °C)

API family

sorbic acid

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

132-135 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

C\C=C\C=C\C(O)=O

InChI

1S/C6H8O2/c1-2-3-4-5-6(7)8/h2-5H,1H3,(H,7,8)/b3-2+,5-4+

InChI key

WSWCOQWTEOXDQX-MQQKCMAXSA-N

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1 of 4

This Item
S09500001.0066282070
Sorbic acid Pharmaceutical Secondary Standard; Certified Reference Material

PHR1367

Sorbic acid

Sorbic acid European Pharmacopoeia (EP) Reference Standard

S0950000

Sorbic acid

Sorbic acid EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, NF, FCC, E 200

1.00662

Sorbic acid

Sorbic acid tested according to Ph. Eur.

82070

Sorbic acid

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

API processing | cocrystal formation: suitable, API processing | salt formation: suitable

technique(s)

-

format

neat

format

neat

format

-

format

-

Quality Level

300

Quality Level

-

Quality Level

500

Quality Level

100

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

-

grade

-

storage temp.

2-30°C

storage temp.

-

storage temp.

15-25°C

storage temp.

-

General description

Sorbic acid is a short-chained unsaturated aliphatic carboxylic fatty acid, that is used as an antimicrobial preservative in a wide range of foods, drugs, and cosmetic products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Sorbic acid may be used as a pharmaceutical reference standard for the determination of the analyte in raw material, food and pharmaceutical formulations by titrimetry and high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2087 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

260.6 °F

flash_point_c

127 °C


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Optimisation of extraction procedures for analysis of benzoic and sorbic acids in foodstuffs
Mota FJM
Food Chemistry, 82(3), 469-473 (2003)
Determination of antimicrobial preservatives in pharmaceutical formulations using reverse-phase liquid chromatography
Radus TP and Gyr G
European Journal of Pharmaceutical Sciences, 72(3), 221-224 (1983)
Determination of antimicrobial preservatives in pharmaceutical formulations using reverse-phase liquid chromatography
Radus TP and Gyr G
Journal of Pharmaceutical Sciences, 72(3), 221-224 (1983)
Wine Analysis and Production
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Sorbic acid
Pharmacopeia, US
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