PHR1398
Betamethasone
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
Betamethasone, 9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16β-methylprednisolone
About This Item
Recommended Products
biological source
synthetic
Quality Level
grade
certified reference material
pharmaceutical secondary standard
agency
BP
EP
USP
traceable to BP 575
traceable to Ph. Eur. B1000000
traceable to USP 1066009
vapor pressure
<0.0000001 kPa ( 25 °C)
API family
betamethasone
CofA
current certificate can be downloaded
packaging
pkg of 1 g
storage condition
protect from light (20 mm aluminium crimp seal for unused portion)
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
color
white to light yellow
mp
235-237 °C (lit.)
solubility
acetone: sparingly soluble
chloroform: very slightly soluble
ethanol: sparingly soluble
ether: very slightly soluble
methanol: sparingly soluble
water: insoluble
density
0.305 g/cm3 at 25 °C (77°F)
application(s)
pharmaceutical (small molecule)
format
neat
shipped in
ambient
storage temp.
2-30°C
SMILES string
[H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
InChI
1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
InChI key
UREBDLICKHMUKA-DVTGEIKXSA-N
Gene Information
human ... NR3C1(2908)
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General description
Betamethasone belongs to the corticosteriod family of active pharmaceutical ingredients (APIs). It exhibits anti-inflammatory activity and hence is used in the manufacture of various finished pharmaceutical products and is also employed as a starting material to manufacture other APIs that are related to this steroid family.
Application
Analysis Note
Other Notes
Footnote
related product
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B - STOT RE 2
target_organs
Liver,Kidney,Endocrine system
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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