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PHR1799

Supelco

Meloxicam

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
Meloxicam, 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
Empirical Formula (Hill Notation):
C14H13N3O4S2
CAS Number:
Molecular Weight:
351.40

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to BP 629
traceable to Ph. Eur. Y0001080
traceable to USP 1379401

API family

meloxicam

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,19H,1-2H3,(H,15,16)/b13-11+

InChI key

DWMREKMVXIFPFM-ACCUITESSA-N

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This Item
PHR2500PHR2327PHR2502
Supelco

PHR1799

Meloxicam

Meloxicam Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material

PHR2500

Meloxicam Related Compound A

Supelco

PHR2327

Meloxicam Impurity C

Supelco

PHR2502

Meloxicam Related Compound C

format

neat

format

-

format

-

format

-

Quality Level

300

Quality Level

300

Quality Level

300

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

packaging

pkg of 500 mg

packaging

pkg of 50 mg

packaging

pkg of 50 mg

packaging

pkg of 50 mg

General description

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Meloxicam is an oxicam derivative and belongs to the group of non-steroidal anti-inflammatory drugs (NSAID), used for its analgesic, anti-inflammatory, and antipyretic properties. It acts by inhibiting the activity of prostaglandin synthetase, thereby preventing the synthesis of prostaglandins and decreasing inflammation.

Application

This pharmaceutical secondary standard can also be used as follows:

  • Development of three spectrophotometric methods to determine meloxicam in its pharmaceutical formulations
  • Voltammetric determination of meloxicam in pharmaceutical formulations using a boron-doped diamond electrode (BDDE)
  • High-performance liquid chromatography-based quantitative analysis of meloxicam in its different tablet formulations
  • Development and validation of a reversed-phase HPLC method for the separation and estimation of meloxicam in its pharmaceutical dosage forms
  • Quantification of meloxicam and piroxicam from plasma samples using a liquid chromatography method combined with UV detection

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB7807 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

related product

Product No.
Description
Pricing

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Meloxicam Related Compound A

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Reverse phase HPLC method development and validation for determination of Meloxicam in bulk and pharmaceutical formulation
Shaji J and Jain V
International Journal of Pharmaceutical Sciences and Research, 2, 107-107 (2011)
Spectrophotometric estimation of meloxicam in bulk and its pharmaceutical formulations
Dhandapani B, et al.
International Journal of Pharma Sciences and Research, 1, 217-221 (2010)
High-performance liquid chromatography determination of meloxicam and piroxicam with ultraviolet detection
Cox S, et al.
Chromatography Research International, 2014 (2014)
Electrochemical oxidation of anti-inflammatory drug meloxicam and its determination using boron doped diamond electrode
Selesovska R, et al.
Journal of Electroanalytical Chemistry, 858, 113758-113758 (2020)
Specific and simple hplc assay of ecofriendly meloxicam in pharmaceutical formulations
Mahmood KT, et al.
Journal of Pharmaceutical Sciences and Research, 2, 878-878 (2010)

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