PHR2363
Menaquinone -7
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
Vitamin K2-(MK-7), (all-E)–2-(3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione
About This Item
Recommended Products
grade
certified reference material
pharmaceutical secondary standard
Quality Level
agency
traceable to USP 1381119
API family
menaquinone
form
solid
CofA
current certificate can be downloaded
packaging
pkg of 3x75 mg
application(s)
pharmaceutical small molecule
storage temp.
-10 to -25°C
InChI
1S/C46H64O2/c1-34(2)18-12-19-35(3)20-13-21-36(4)22-14-23-37(5)24-15-25-38(6)26-16-27-39(7)28-17-29-40(8)32-33-42-41(9)45(47)43-30-10-11-31-44(43)46(42)48/h10-11,18,20,22,24,26,28,30-32H,12-17,19,21,23,25,27,29,33H2,1-9H3/b35-20+,36-22+,37-24+,38-26+,39-28+,40-32+
InChI key
RAKQPZMEYJZGPI-LJWNYQGCSA-N
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General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Menaquinone -7 is a naphthoquinone derivative and one of the most active sub-type of vitamin K2, with 7 referring to the number of isoprene units in its structure. It is naturally found in fermented dairy products and is considered a nutrient, thereby being found as a component of various nutritional supplements.
Application
- Ultra high-performance liquid chromatography (UHPLC) based determination of menaquinone-7 and vitamin D3 in their combined tablet formulation
- Development of a thin-layer chromatographic-densitometric technique for the quantitative analysis of vitamins K and D3 in pharmaceutical tablet formulations and dietary supplements
- Simultaneous determination of vitamin D3 and K2 (Menaquinone-4 and Menaquinone-7) in dietary supplements by ultra-high-pressure liquid chromatography (UHPLC)
- Impurity profiling of menaquinone-7 in its active pharmaceutical ingredient (API) samples using HPLC coupled to UV detector
- Analysis of menaquinone-4 and menaquinone-7 by HPLC in combination with tandem mass spectrometry (MS/MS) in human milk samples
Analysis Note
Footnote
Recommended products
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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