S0883
Sulfasalazine
97.0-101.5%
Synonym(s):
2-Hydroxy-5-{{4-[(2-pyridinylamino)sulfonyl]phenyl}azo}benzoic acid, 5-[4-(2-Pyridylsulfamoyl)phenylazo]salicylic acid, Salicylazosulfapyridine
About This Item
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Quality Level
assay
97.0-101.5%
form
powder
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
260-265 °C (dec.) (lit.)
application(s)
forensics and toxicology
pharmaceutical (small molecule)
mode of action
DNA synthesis | interferes
enzyme | inhibits
SMILES string
OC(=O)c1cc(ccc1O)\N=N\c2ccc(cc2)S(=O)(=O)Nc3ccccn3
InChI
1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,23H,(H,19,22)(H,24,25)/b21-20+
InChI key
NCEXYHBECQHGNR-QZQOTICOSA-N
Gene Information
human ... ALOX5(240) , PTGS1(5742) , PTGS2(5743)
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General description
Application
- For investigating its therapeutic potential in patients suffering from multiple sclerosis (MS).
- For studying its role as an antiarthritic agent via inhibition of the cartilage degeneration and pain associated with progression of osteoarthritis in the rat, which is used as the test animal.
It may also be used as an analytical reference standard for the quantification of the analyte in biological samples and aqueous samples using enzyme-linked immunosorbent assay (ELISA) and spectrofluorimetic technique.
signalword
Danger
Hazard Classifications
Aquatic Chronic 2 - Carc. 2 - Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
wgk_germany
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Certificates of Analysis (COA)
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