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Key Documents

S2200000

Suxamethonium chloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Succinylcholine chloride dihydrate, Bis(trimethylammonioethyl) succinate chloride, Succinyldicholine dichloride

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About This Item

Linear Formula:
[(CH3)3NCH2CH2OCOCH2]2Cl2 · 2H2O
CAS Number:
Molecular Weight:
397.34
Beilstein/REAXYS Number:
3922827
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

succinylcholine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O.O.[Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C

InChI

1S/C14H30N2O4.2ClH.2H2O/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;;;/h7-12H2,1-6H3;2*1H;2*1H2/q+2;;;;/p-2

InChI key

FFSBEIRFVXGRPR-UHFFFAOYSA-L

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Suxamethonium chloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable


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Use of suxamethonium in open eye injuries: a dilemma with explosive consequences.
Meena Arunakirinathan et al.
British journal of hospital medicine (London, England : 2005), 75(7), 418-418 (2014-07-22)
Alice E McGovern et al.
British journal of pharmacology, 171(15), 3633-3650 (2014-04-26)
Subtypes of the hyperpolarization-activated cyclic nucleotide-gated (HCN) family of cation channels are widely expressed on nerves and smooth muscle cells in many organ systems, where they serve to regulate membrane excitability. Here we have assessed whether HCN channel inhibitors alter

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