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Y0001138

Phenazone impurity A

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

3-Methyl-1-phenyl-2-pyrazoline-5-one, 5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one

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About This Item

Empirical Formula (Hill Notation):
C10H10N2O
CAS Number:
89-25-8
Molecular Weight:
174.20
Beilstein/REAXYS Number:
609575
MDL number:
MFCD00003138
UNSPSC Code:
41116107
PubChem Substance ID:
329830780
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

phenazone

manufacturer/tradename

EDQM

bp

287 °C/265 mmHg (lit.)

mp

126-128 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC1=NN(C(=O)C1)c2ccccc2

InChI

1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3

InChI key

QELUYTUMUWHWMC-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Phenazone impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

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Description
Pricing

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

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PloS one, 9(6), e99219-e99219 (2014-06-05)
Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a free radical scavenger, is used for the clinical treatment of retinal injury. In this study, we investigated the protective effects of edaravone against diabetic retinal damage in the mouse. Diabetic retinopathy in the mouse was induced by
Fahui Zhao et al.
Neurosciences (Riyadh, Saudi Arabia), 19(2), 106-110 (2014-04-18)
To explore the effects of edaravone on the expression of matrix metalloproteinase-9 (MMP-9) posterior to cerebral hemorrhage, and to analyze the relationship between this expression and neurological deficit. A total of 160 basal ganglia hemorrhage patients enrolled in Dongfeng Hospital
Yu-Ichi Aoyama et al.
Journal of UOEH, 36(4), 289-294 (2014-12-17)
A 51 year old male was admitted to our hospital with sudden consciousness disturbance, global aphagia and right hemiparesis. Magnetic resonance imaging (MRI) revealed fresh infarctions in the territory of the left middle cerebral artery, and MR angiography (MRA) showed
Byeongtaek Oh et al.
Pharmaceutical research, 31(9), 2463-2478 (2014-03-26)
The nanofiber-hydrogel blend containing nitric oxide (NO) donors and reactive oxygen species (ROS) scavengers (Edaravone: EDV) was explored as an advanced strategy for stabilization of Mast cells (MCs) to achieve efficient immune-suppressive effects. Three types of nanofiber hydrogel composites (Bare-Nanofibers
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