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03129

Sigma-Aldrich

Sodium iodide

puriss., meets analytical specification of Ph. Eur., BP, USP, 99-100.5% (calc. to the dried substance)

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About This Item

Linear Formula:
NaI
CAS Number:
Molecular Weight:
149.89
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NB.22

vapor density

>1 (vs air)

Quality Level

grade

puriss.

assay

99-100.5% (calc. to the dried substance)

form

crystalline

quality

meets analytical specification of Ph. Eur., BP, USP

impurities

alkalic reac. Impurities, complies
barium and thiosulfate, complies
organic volatile impurities, complies (GC)
residual solvents, in accordance
≤0.0005% heavy metals (as Pb)
≤0.003% total nitrogen (N)
≤0.005% thiosulfate (S2O3)
≤0.02% free alkali (as NaOH)
≤2% water (Karl Fischer)

loss

≤2% loss on drying, 105 °C

pH

6-9 (20 °C, 50 g/L)

mp

661 °C (lit.)

anion traces

bromide, chloride (as Cl-): ≤300 mg/kg
iodate (IO3-): ≤2 mg/kg
sulfate (SO42-): ≤100 mg/kg

cation traces

Fe: ≤5 mg/kg
K: ≤500 mg/kg

suitability

complies for appearance of solution

SMILES string

[Na+].[I-]

InChI

1S/HI.Na/h1H;/q;+1/p-1

InChI key

FVAUCKIRQBBSSJ-UHFFFAOYSA-M

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General description

Sodium iodide is an inorganic salt. Mixture of chlorotrimethylsilane/sodium iodide in acetonitrile is a useful reagent for the cleavage of esters, lactones, carbamates and ethers.

Application

Sodium iodide may be used in the preparation of sodium hydroxide-sodium iodide reagent for the modified Winkler method for the determination of dissolved oxygen. It may be used for the synthesis of coppersensor-1 (CS1), a membrane-permeable fluorescent dye used for imaging labile copper pools in biological samples.

Caution

may contain black particle through the manufacture

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Evan W Miller et al.
Nature protocols, 1(2), 824-827 (2007-04-05)
Coppersensor-1 (CS1) is a small-molecule, membrane-permeable fluorescent dye for imaging labile copper pools in biological samples, including live cells. This probe, comprising a boron dipyrromethene (BODIPY) chromophore coupled to a thioether-rich receptor, has a picomolar affinity for Cu+ with high
Synthetic methods and reactions. 62. Transformations with chlorotrimethylsilane/sodium iodide, a convenient in situ iodotrimethylsilane reagent.
Olah GA, et al.
The Journal of Organic Chemistry, 44(8), 1247-1251 (1979)
The Chesapeake Bay Institute technique for the Winkler dissolved oxygen method.
Carpenter JH.
Limnology and Oceanography, 10(1), 141-143 (1965)
Caroline Serrano-Nascimento et al.
Molecular and cellular endocrinology, 349(2), 154-161 (2011-10-18)
Iodide excess acutely downregulates NIS mRNA expression, as already demonstrated. PCCl3 cells treated or not with NaI, NaI+NaClO(4) or NaI+Methimazole, for 30 min to 24 h, were used to further explore how iodide reduces NIS gene expression. NIS mRNA expression
Lan-Tao Li et al.
Chemical communications (Cambridge, England), 48(42), 5187-5189 (2012-04-20)
nBu(4)NI-catalyzed C3-selective formylation of N-H and N-substituted indoles by using N-methylaniline as a formylating reagent was first successfully demonstrated.

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