33147

1,4-Dioxane

puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5% (GC)

• Synonym(s): Diethylene oxide, Dioxane
• Empirical Formula (Hill Notation): C₄H₈O₂
• CAS Number: 123-91-1
• Molecular Weight: 88.11
• Beilstein/REAXYS Number: 102551
• EC Number: 204-661-8
• MDL number: MFCD00006571
• UNSPSC Code: 12352005
• PubChem Substance ID: 329754462
• NACRES: NA.21

Properties

• grade: ACS reagent; puriss. p.a.
• agency: USP/NF; reag. ISO; reag. Ph. Eur.
• vapor density: 3 (vs air)
• vapor pressure: 27 mmHg ( 20 °C); 40 mmHg ( 25 °C)
• assay: ≥99.5% (GC)
• form: liquid
• autoignition temp.: 356 °F
• contains: ~25 mg/L 2,6-di-tert.-butyl-4-methylphenol as stabilizer
• expl. lim.: 22 %
• impurities: ≤0.001% free acid (as CH₃COOH); ≤0.001% non-volatile matter; ≤0.005% acetaldehyde; ≤0.005% peroxides (as H₂O₂); ≤0.01% carbonyl compounds (as HCHO); ≤0.05% water (Karl Fischer)
• refractive index: n20/D 1.4210-1.4240; n20/D 1.422 (lit.)
• pH: 6.0-8 (20 °C, 500 g/L)
• bp: 100-102 °C (lit.)
• mp: 10-12 °C (lit.)
• transition temp: solidification point ≤11 °C
• density: 1.034 g/mL at 25 °C (lit.)
• cation traces: Al: ≤0.5 mg/kg; B: ≤0.02 mg/kg; Ba: ≤0.1 mg/kg; Ca: ≤0.5 mg/kg; Cd: ≤0.05 mg/kg; Co: ≤0.02 mg/kg; Cr: ≤0.02 mg/kg; Cu: ≤0.02 mg/kg; Fe: ≤0.1 mg/kg; Mg: ≤0.1 mg/kg; Mn: ≤0.02 mg/kg; Ni: ≤0.02 mg/kg; Pb: ≤0.1 mg/kg; Sn: ≤0.1 mg/kg; Zn: ≤0.1 mg/kg
• SMILES string: C1COCCO1
• InChI: 1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2
• InChI key: RYHBNJHYFVUHQT-UHFFFAOYSA-N

Description

General description

1,4-Dioxane is widely used as a solvent for various organic compounds in industry. It is a non-biodegradable contaminant found in industrial effluents. Oxidative degradation of 1,4-dioxane by using oxygen and ozone has been useful in converting it into biodegradable products, which can be easily removed by conventional methods.

Application

1,4-Dioxane has been employed as a solvent in the synthesis of N-(4-(prop-2-ynyloxy)phenyl)acetamide and 3-(4-(prop-2-ynyloxy)phenyl)-3,4-dihydro-2H-benzo[e][1,3]oxazine.

Other Notes

The article number 33147-6X1L will be discontinued. Please order the single bottle 33147-1L which is physically identical with the same exact specifications.

Safety Information

• pictograms: GHS02,GHS08,GHS07
• signalword: Danger
• hcodes: H225,H319,H335,H350
• pcodes: P202 - P210 - P233 - P240 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• target_organs: Respiratory system
• supp_hazards: EUH019,EUH066
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 51.8 °F - closed cup
• flash_point_c: 11 °C - closed cup