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33147

Sigma-Aldrich

1,4-Dioxane

puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5% (GC)

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Synonym(s):
Diethylene oxide, Dioxane
Empirical Formula (Hill Notation):
C4H8O2
CAS Number:
Molecular Weight:
88.11
Beilstein/REAXYS Number:
102551
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent
puriss. p.a.

Quality Level

agency

USP/NF
reag. ISO
reag. Ph. Eur.

vapor density

3 (vs air)

vapor pressure

27 mmHg ( 20 °C)
40 mmHg ( 25 °C)

assay

≥99.5% (GC)

form

liquid

autoignition temp.

356 °F

contains

~25 mg/L 2,6-di-tert.-butyl-4-methylphenol as stabilizer

expl. lim.

22 %

impurities

≤0.001% free acid (as CH3COOH)
≤0.001% non-volatile matter
≤0.005% acetaldehyde
≤0.005% peroxides (as H2O2)
≤0.01% carbonyl compounds (as HCHO)
≤0.05% water (Karl Fischer)

refractive index

n20/D 1.4210-1.4240
n20/D 1.422 (lit.)

pH

6.0-8 (20 °C, 500 g/L)

bp

100-102 °C (lit.)

mp

10-12 °C (lit.)

transition temp

solidification point ≤11 °C

density

1.034 g/mL at 25 °C (lit.)

cation traces

Al: ≤0.5 mg/kg
B: ≤0.02 mg/kg
Ba: ≤0.1 mg/kg
Ca: ≤0.5 mg/kg
Cd: ≤0.05 mg/kg
Co: ≤0.02 mg/kg
Cr: ≤0.02 mg/kg
Cu: ≤0.02 mg/kg
Fe: ≤0.1 mg/kg
Mg: ≤0.1 mg/kg
Mn: ≤0.02 mg/kg
Ni: ≤0.02 mg/kg
Pb: ≤0.1 mg/kg
Sn: ≤0.1 mg/kg
Zn: ≤0.1 mg/kg

SMILES string

C1COCCO1

InChI

1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2

InChI key

RYHBNJHYFVUHQT-UHFFFAOYSA-N

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1 of 4

This Item
360481PHR1549296309
1,4-Dioxane puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5% (GC)

33147

1,4-Dioxane

Essential Grade
1,4-Dioxane ACS reagent, ≥99.0%, contains ≤25 ppm BHT as stabilizer

360481

1,4-Dioxane

-
1,4-Dioxane Pharmaceutical Secondary Standard; Certified Reference Material

PHR1549

1,4-Dioxane

-
1,4-Dioxane anhydrous, 99.8%, contains <=25 ppm BHT as stabilizer

296309

1,4-Dioxane

-
grade

ACS reagent, puriss. p.a.

grade

ACS reagent

grade

certified reference material, pharmaceutical secondary standard

grade

anhydrous

form

liquid

form

liquid

form

-

form

liquid

density

1.034 g/mL at 25 °C (lit.)

density

1.034 g/mL at 25 °C (lit.)

density

1.034 g/mL at 25 °C (lit.)

density

1.034 g/mL at 25 °C (lit.)

expl. lim.

22 %

expl. lim.

22 %

expl. lim.

22 %

expl. lim.

22 %

mp

10-12 °C (lit.)

mp

10-12 °C (lit.)

mp

10-12 °C (lit.)

mp

10-12 °C (lit.)

General description

1,4-Dioxane is widely used as a solvent for various organic compounds in industry. It is a non-biodegradable contaminant found in industrial effluents. Oxidative degradation of 1,4-dioxane by using oxygen and ozone has been useful in converting it into biodegradable products, which can be easily removed by conventional methods.

Application

1,4-Dioxane has been employed as a solvent in the synthesis of N-(4-(prop-2-ynyloxy)phenyl)acetamide and 3-(4-(prop-2-ynyloxy)phenyl)-3,4-dihydro-2H-benzo[e][1,3]oxazine.

Other Notes

The article number 33147-6X1L will be discontinued. Please order the single bottle 33147-1L which is physically identical with the same exact specifications.

signalword

Danger

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Respiratory system

supp_hazards

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup


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