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M1880

Sigma-Aldrich

Magnesium sulfate heptahydrate

ReagentPlus®, ≥99.0%

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Synonym(s):
Epsom salts
Linear Formula:
MgSO4 · 7H2O
CAS Number:
Molecular Weight:
246.47
EC Number:
MDL number:
eCl@ss:
38030409
PubChem Substance ID:
NACRES:
NA.21

vapor density

<0.01 (vs air)

Quality Level

vapor pressure

<0.1 mmHg ( 20 °C)

product line

ReagentPlus®

Assay

≥99.0%

form

powder or crystals

pH

5-8 (50 g/L)

SMILES string

O.O.O.O.O.O.O.[Mg++].[O-]S([O-])(=O)=O

InChI

1S/Mg.H2O4S.7H2O/c;1-5(2,3)4;;;;;;;/h;(H2,1,2,3,4);7*1H2/q+2;;;;;;;;/p-2

InChI key

WRUGWIBCXHJTDG-UHFFFAOYSA-L

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This Item
2303916314063138
Magnesium sulfate heptahydrate ACS reagent, &#8805;98%

Sigma-Aldrich

230391

Magnesium sulfate heptahydrate

Essential Grade
Magnesium sulfate heptahydrate puriss. p.a., ACS reagent, &#8805;99.0% (KT)

Sigma-Aldrich

63140

Magnesium sulfate heptahydrate

Essential Grade
Magnesium sulfate heptahydrate BioUltra, &#8805;99.5% (KT)

Sigma-Aldrich

63138

Magnesium sulfate heptahydrate

Premium Grade
assay

≥99.0%

assay

≥98%, 98.0-102.0% (ACS specification)

assay

≥99.0% (KT)

assay

≥99.5% (KT)

form

powder or crystals

form

crystals

form

powder or crystals

form

-

pH

5-8 (50 g/L)

pH

5.0-8.2 (25 °C, 5%)

pH

5.0-8.2 (25 °C, 50 mg/mL in H2O)

pH

5.0-8.0 (25 °C, 1 M in H2O)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

vapor density

<0.01 (vs air)

vapor density

<0.01 (vs air)

vapor density

<0.01 (vs air)

vapor density

<0.01 (vs air)

General description

Magnesium sulfate heptahydrate is hydrated salt of magnesium sulfate. It is hygroscopic in its anhydrous form. It can be used as a hydrophilic additive and as a catalyst in organic synthesis.

Application

Magnesium sulfate heptahydrate is used:
  • As an effective,catalyst for the condensation of o-phenylenediamine and 1,2-dicarbonyl compounds at room temperature.
  • As a catalyst in the synthesis of tri/tetra-substituted imidazoles from wide range of aromatic aldehydes, benzil, aliphatic and aromatic primary amines and ammonium acetate.
  • In the preparation of amorphous magnesium borates of various composition by interacting with sodium borate decahydrate.

Magnesium sulfate heptahydrate may be used as a catalyst for the condensation of o-phenylenediamines with 1,2-dicarbonyl compounds to form phenazine and quinoxaline derivatives. It may also be used as a catalyst along with indium (III) triflate for the synthesis of tri/tetra-substituted imidazoles.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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New conditions for the effective synthesis of tri and tetrasubstituted imidazoles catalysed by recyclable indium (III) triflate and magnesium sulfate heptahydrate.
Karami B, et al.
J. Chem. Res. (M), 38(1), 41-45 (2014)
A facile synthesis of phenazine and quinoxaline (new 1,4-benzo diazine) derivatives using magnesium sulfate heptahydrate as a catalyst.
Karami B and Khodabakhshi S.
J. Serb. Chem. Soc., 76(9), 1191-1198 (2011)
Size-dependent growth of magnesium sulfate heptahydrate.
Rousseau RW and Parks RM.
Industrial & Engineering Chemistry Fundamentals, 20(1), 71-76 (1981)
Shoshana Naiman et al.
Cell reports, 29(12), 4127-4143 (2019-12-19)
The pro-longevity enzyme SIRT6 regulates various metabolic pathways. Gene expression analyses in SIRT6 heterozygotic mice identify significant decreases in PPARα signaling, known to regulate multiple metabolic pathways. SIRT6 binds PPARα and its response element within promoter regions and activates gene transcription.
Ran D Goldman et al.
Pediatrics, 132(6), e1634-e1641 (2013-11-28)
Vaso-occlusive episodes (VOEs) are the most common complication of sickle cell disease in children. Treatment with magnesium seems to improve cellular hydration and may result in reduced vaso-occlusion. This study aimed to determine if intravenous (IV) magnesium sulfate (MgSO4) reduces

Protocols

To measure luciferase activity, an assay that measures light emission with a luminometer is used. Firefly luciferase is used for detection and quantitation of ATP and as a reporter for genetic function.

To measure 5′-nucleotidase activity, this procedure uses adenosine 5’-monophosphate and a color reagent to create a standard curve for determining the micromoles of phosphorus liberated.

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