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100-05N

Sigma-Aldrich

Human Dermal Microvascular Endothelial Cells: CADMEC/HMVEC, neonatal

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NACRES:
NA.81

biological source

human neonatal foreskin or adult skin capillaries (normal)

Quality Level

packaging

pkg of 500,000 cells

manufacturer/tradename

Cell Applications, Inc

growth mode

Adherent

karyotype

2n = 46

morphology

Endothelial

technique(s)

cell culture | mammalian: suitable

shipped in

dry ice

storage temp.

−196°C

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This Item
100-05AS100-05AS100-05N
biological source

human neonatal foreskin or adult skin capillaries (normal)

biological source

human neonatal foreskin or adult skin capillaries (normal)

biological source

human blood vessels

biological source

human blood vessels

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

growth mode

Adherent

growth mode

Adherent

growth mode

Adherent

growth mode

Adherent

karyotype

2n = 46

karyotype

2n = 46

karyotype

2n = 46

karyotype

2n = 46

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

General description

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

CADMEC/HMVEC provide an excellent model system to study many aspects of endothelial function and disease, especially those related to the microvasculature and capillary systems. HMVEC/CADMEC have been shown to express vWF, CD36 and CD31, are able to uptake DiI-Ac-LDL and are positive for functional activity by cytokine-stimulated leukocyte adherence.

Select HMVEC lots have been additionally tested to demonstrate stimulation-dependent angiogenesis and key endothelial cell signaling pathways (phosphorylation of VEGFR, Akt, MAPK, and expression of Tie2, eNOS, Axl and Etk/Bmx).

Cell Line Origin

Skin

Application

Endothelial vessel function, cell signaling, angiogenesis

Components

Cell Basal Medium containing 10% FBS & 10% DMSO

Preparation Note

  • 2nd passage, >500,000 cells in Cell Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 16 doublings

Subculture Routine

Please refer to the CADMEC/HMVEC Culture Protocol.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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