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O-Methyl-O′-succinylpolyethylene glycol 2′000

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Synonym(s):
Polyethylene glycol, O-(Succinyl)-O′-methylpolyethylene glycol 2′000, Polyethylene glycol 2′000 monomethyl ether succinate
Linear Formula:
CH3O(CH2CH2O)nCOCH2CH2COOH
CAS Number:
MDL number:
NACRES:
NA.26

form

powder

Quality Level

mol wt

Mr ~2100

mp

50-53 °C

Ω-end

carboxylic acid

α-end

methoxy

storage temp.

−20°C

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Poly(ethylene glycol) methyl ether average Mn 5,000

81323

Poly(ethylene glycol) methyl ether

Poly(ethylene glycol) methyl ether average Mn 20,000

732613

Poly(ethylene glycol) methyl ether

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

mol wt

Mr ~2100

mol wt

average Mn 5,000

mol wt

Mr ~5100

mol wt

average Mn 20,000

Ω-end

carboxylic acid

Ω-end

hydroxyl

Ω-end

carboxylic acid

Ω-end

hydroxyl

α-end

methoxy

α-end

methoxy

α-end

methoxy

α-end

methoxy

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

storage temp.

−20°C

Application

Polyethylene glycol 2000 is used in the construction of biomaterials such as biopolymers, micelles and nanostructures.

Biochem/physiol Actions

O-Methyl-O′-succinylpolyethylene glycol 2′000 is a modified monomethoxypolyethylene glycol (mPEG) wherein the hydroxyl groups are succinylated by succinic anhydride. This succinylated mPEG can then be used to synthesize tolerogenic mPEG conjugates of peptides. Tolerogenic peptide conjugates are very effective reagents for obtaining epitope-specific immunosuppression of antibody responses to immunopathogenic sites on multideterminant complex protein antigens.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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