MilliporeSigma
All Photos(1)

Documents

389M-1

Sigma-Aldrich

Glutamine Synthetase (GS-6) Mouse Monoclonal Antibody

Sign Into View Organizational & Contract Pricing

NACRES:
NA.41

biological source

mouse

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

GS-6, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (389M-14)
vial of 0.5 mL concentrate (389M-15)
bottle of 1.0 mL predilute (389M-17)
vial of 1.0 mL concentrate (389M-16)
bottle of 7.0 mL predilute (389M-18)

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotype

IgG2a

control

hepatocellular carcinoma

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... GLUL(2752)

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
MABN1182MAB302SAB5701312
conjugate

unconjugated

conjugate

-

conjugate

-

conjugate

-

species reactivity

human

species reactivity

human, rat

species reactivity

human, rat, mouse, sheep

species reactivity

rat, mouse, human

antibody form

culture supernatant

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

-

biological source

mouse

biological source

mouse

biological source

mouse

biological source

rabbit

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

technique(s)

immunohistochemistry: suitable (paraffin), western blot: suitable

technique(s)

ELISA: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, western blot: suitable

technique(s)

immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000

Still not finding the right product?  

Give our Product Selector Tool a try.

General description

Glutamine synthetase (GS) catalyzes the synthesis of glutamine from glutamate and ammonia in the mammalian liver. In normal liver, GS expression is seen in centrilobular (zone 3) hepatocytes, but not in mid-zone (zone 2) or periportal (zone 3) hepatocytes. Glutamine synthetase immunohistochemistry is also positive in neoplasms of hepatocyte origin, such as hepatocellular carcinoma (HCC) and hepatocellular adenoma, making it useful for identifying these tumors.

Quality


IVD

IVD

IVD

RUO

Linkage

Glutamine Synthetase Positive Control Slides, Product No. 389S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Luca Di Tommaso et al.
Hepatology (Baltimore, Md.), 45(3), 725-734 (2007-02-28)
Hepatocellular nodules in cirrhosis include regenerative (large regenerative, LRN) and dysplastic (low and high grade, LGDN and HGDN) nodules, early and grade 1 HCC (eHCC-G1), and overt HCC. The differential diagnosis may be particularly difficult when lesions such as HGDN

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service