Skip to Content
MilliporeSigma
All Photos(1)

Documents

85451

Sigma-Aldrich

β-Sitosterol

≥70%

Synonym(s):

α-Dihydrofucosterol, 22,23-Dihydrostigmasterol, 24α-Ethylcholesterol, 5-Stigmasten-3β-ol

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C29H50O
CAS Number:
Molecular Weight:
414.71
Beilstein/REAXYS Number:
1916165
EC Number:
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.77

biological source

plant

Quality Level

assay

≥70%

form

powder

impurities

campesterol and β-sitostanol, residual

mp

136-140 °C (lit.)

functional group

hydroxyl

SMILES string

O[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CC[C@H](C(C)C)CC

InChI

1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1

InChI key

KZJWDPNRJALLNS-VJSFXXLFSA-N

Looking for similar products? Visit Product Comparison Guide

Application

β-Sitosterol was used to supplement diet of mice to study its effect on body mass accumulation.

Biochem/physiol Actions

β-Sitosterol is a plant sterol that has hypocholesterolemic activity. Only 5% of β-Sitosterol is absorbed by humans. It is hypothesized that the cholesterol-lowering activity is by competing cholesterol for uptake by the cells or by interfering with the esterification of cholesterol. β-Sitosterol is reported to reduce the incidence of colon tumors.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Dietary supplementation with phytosterol and ascorbic acid reduces body mass accumulation and alters food transit time in a diet-induced obesity mouse model
Thornton SJ et al
Lipids in Health and Disease, 10, doi: 10-doi: 10 (2011)
Pauline Seguinot et al.
International journal of food microbiology, 316, 108441-108441 (2019-11-30)
Even though non-Saccharomyces yeasts were regarded as spoilage microorganisms for a long time, their abilities to improve and diversify the aromatic profile of wines are now well recognized. Consequently, their use in combination with S. cerevisiae strains during winemaking has
Yoshihide Yamanashi et al.
The Journal of pharmacology and experimental therapeutics, 320(2), 559-564 (2006-12-01)
Previous in vivo studies including those with knockout mice suggested that Niemann-Pick C1-like 1 (NPC1L1) plays an essential role in the intestinal absorption of cholesterol. To characterize the mechanism of cholesterol uptake mediated by NPC1L1, an in vitro system reflecting
F J Field et al.
Journal of lipid research, 24(4), 409-417 (1983-04-01)
Rabbits were fed either 10% coconut oil, 10% coconut oil and 1% beta-sitosterol, 10% coconut oil and 1% cholesterol, or 10% coconut oil and 1% beta-sitosterol plus 1% cholesterol for 4 weeks. Microsomal membranes from intestines of animals fed the
Oliver Harlé et al.
PloS one, 15(5), e0233285-e0233285 (2020-05-27)
Fermentation by microorganisms is a key step in the production of traditional food products such as bread, cheese, beer and wine. In these fermentative ecosystems, microorganisms interact in various ways, namely competition, predation, commensalism and mutualism. Traditional wine fermentation is

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service