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86339

Sigma-Aldrich

Sodium taurocholate hydrate

≥97.0% (TLC)

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Synonym(s):
Taurocholic acid sodium salt
Empirical Formula (Hill Notation):
C26H44NNaO7S · xH2O
CAS Number:
Molecular Weight:
537.68 (anhydrous basis)
Beilstein/REAXYS Number:
3901620
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

biological source

ox bile
synthetic

Quality Level

description

anionic

assay

≥97.0% (TLC)

form

powder

optical activity

[α]20/D +23±1°, c = 3% in H2O (dry matter)

mol wt

537.68 g/mol (anhydrous basis)

impurities

≤1% taurine
≤2% cholic acid

solubility

H2O: 50 mg/mL, clear

functional group

sulfonic acid

SMILES string

O.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1

InChI key

RDAJAQDLEFHVNR-NEMAEHQESA-M

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This Item
900036O013651738
Sodium taurocholate hydrate ≥97.0% (TLC)

86339

Sodium taurocholate hydrate

Sodium taurocholate-2,2,4,4-d4 ≥98 atom % D, ≥98% (CP)

900036

Sodium taurocholate-2,2,4,4-d4

Sodium oxalate BioXtra

O0136

Sodium oxalate

L-Glyceric acid sodium salt ≥95.0% (TLC)

51738

L-Glyceric acid sodium salt

form

powder

form

powder

form

powder

form

powder or crystals

mol wt

537.68 g/mol (anhydrous basis)

mol wt

-

mol wt

-

mol wt

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

biological source

ox bile, synthetic

biological source

-

biological source

-

biological source

-

solubility

H2O: 50 mg/mL, clear

solubility

-

solubility

-

solubility

-

Application

Sodium taurocholate hydrate was used as an emulsifier in in situ preparation of digestive enzymes.

Biochem/physiol Actions

Taurocholic acid is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and deoxycholic acid. These are reabsorbed by the liver via a carrier-mediated process and converted by liver enzymes to taurocholic acid.

Preparation Note

Sodium taurocholate hydrate yields a clear, colorless solution in water at 50 mg/ml.

Other Notes

For the solubilization of unconjugated bilirubin

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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