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A6414

Sigma-Aldrich

Albumin from rat serum

lyophilized powder, essentially fatty acid free, essentially globulin free, ≥99% (agarose gel electrophoresis)

Synonym(s):

RSA, Rat albumin

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About This Item

CAS Number:
9048-46-8
EC Number:
232-936-2
MDL number:
MFCD00804575
UNSPSC Code:
12352202
NACRES:
NA.27

biological source

rat

assay

≥99% (agarose gel electrophoresis)

form

lyophilized powder

technique(s)

ELISA: suitable
tissue culture: suitable
western blot: suitable

UniProt accession no.

P02770

storage temp.

2-8°C

Gene Information

rat ... ALB(24186)

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General description

Albumin is the most abundant plasma protein in humans. Albumin turnover is seen in infants with iron deficiency anemia. Serum albumin is a reliable prognostic indicator for liver disease. Oxidative damage of albumin is associated with advanced liver disease.

Application

Albumin from rat serum has been used:
  • to study its sequence information from multiply charged ions formed by electrospray ionization
  • to cross-link with silk fibroin (SF) to synthesize a combined protein template
  • to infused into the brain to study its effects on nerve cell damage following brain injury

Preparation Note

Prepared from essentially globulin free albumin (A4538).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Erica Polo-Hernández et al.
Journal of neurochemistry, 114(6), 1756-1766 (2010-07-16)
Our previous works showed that oleic acid synthesized in vitro by astrocytes in response to albumin behaves as a neurotrophic factor in neurons, up-regulating several proteins, such as the axonal growth marker growth-associated protein 43(GAP-43). Although the molecular mechanism of
Is calcium accumulation post-injury an indicator of cell damage?
Mechanisms of Secondary Brain Damage in Cerebral Ischemia and Trauma, 15-20 (1996)
Chimeric protein template-induced shape control of bone mineral nanoparticles and its impact on mesenchymal stem cell fate
Wang J, et al.
Biomacromolecules, 16(7), 1987-1996 (2015)
Tandem mass spectrometry of very large molecules: serum albumin sequence information from multiply charged ions formed by electrospray ionization
Loo JA, et al.
Analytical Chemistry, 63(21), 2488-2499 (1991)
Anne Skøttrup Mørkholt et al.
Scientific reports, 8(1), 7092-7092 (2018-05-08)
Multiple sclerosis (MS) is a neurodegenerative autoimmune disease, where chronic inflammation plays an essential role in its pathology. A feature of MS is the production of autoantibodies stimulated by an altered-peptide-ligand response and epitope spreading, resulting in loss of tolerance
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