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Key Documents

AV02023

Sigma-Aldrich

Anti-DIABLO antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-Diablo homolog (Drosophila)

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

21 kDa

species reactivity

human

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_063940

UniProt accession no.

Q9NR28

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DIABLO(56616)

General description

DIABLO is known to interact with mammalian IAP homolog A (MIHA, XIAP), MIHB, MIHC and OpIAP. Furthermore, DIABLO binds to IAPs and prevents them from blocking caspases, thereby inducing apoptosis.
Rabbit Anti-DIABLO antibody binds to human, bovine, pig, and canine DIABLO.

Immunogen

Synthetic peptide directed towards the C terminal region of human DIABLO

Application

Rabbit Anti-DIABLO antibody can be used for western blot applications at 0.3125μg/ml.

Sequence

Synthetic peptide located within the following region: LVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRE

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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A M Verhagen et al.
Cell, 102(1), 43-53 (2000-08-10)
To identify proteins that bind mammalian IAP homolog A (MIHA, also known as XIAP), we used coimmuno-precipitation and 2D immobilized pH gradient/SDS PAGE, followed by electrospray ionization tandem mass spectrometry. DIABLO (direct IAP binding protein with low pI) is a

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