Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

B162

Sigma-Aldrich

B-HT 920 dihydrochloride

solid, ≥98% (HPLC)

Synonym(s):

5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride, Talipexole

Sign Into View Organizational & Contract Pricing

Select a Size

All Photos(1)

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C10H15N3S · 2HCl
CAS Number:
36085-73-1
Molecular Weight:
282.23
MDL number:
MFCD00274573
UNSPSC Code:
12352202
PubChem Substance ID:
24891601

assay

≥98% (HPLC)

form

solid

color

off-white

solubility

H2O: >20 mg/mL

SMILES string

Cl.Cl.Nc1nc2CCN(CCc2s1)CC=C

InChI

1S/C10H15N3S.2ClH/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8;;/h2H,1,3-7H2,(H2,11,12);2*1H

InChI key

DPQAXNSOFFYKDS-UHFFFAOYSA-N

Gene Information

rat ... Drd2(24318)

Biochem/physiol Actions

α2-adrenoceptor agonist; D2 dopamine receptor agonist.

Features and Benefits

This compound is featured on the α2-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
028K4703
023K4700
014K4702

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Kazuo Yamashiro et al.
Movement disorders : official journal of the Movement Disorder Society, 23(7), 935-941 (2008-04-10)
To investigate the frequency of cardiac valve regurgitation related with low dose dopamine agonists in patients with Parkinson's disease (PD), echocardiograms were analyzed in 527 consecutive PD patients (448 patients treated with dopamine agonists, 79 patients never treated with dopamine
Beatriz Civantos et al.
European journal of pharmacology, 489(1-2), 101-110 (2004-04-06)
It has been suggested that the combination of dietary Ca and Ca2+ channel antagonists could have a synergic antihypertensive effect. In this study, 3-week-old male spontaneously hypertensive rats (SHR) were randomized into four groups of animals. Two of these groups
Yoshitoki Takagawa et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 25(2), 197-202 (2002-06-06)
To investigate the vascular endothelial dysfunction in the insulin resistance syndrome, muscarinic and alpha2-adrenergic mediated relaxations were studied in the fructose-fed rat. Male Sprague-Dawley rats were fed either fructose-rich chow (FFR, n=14) or normal chow (CNT, n=13) for 8 weeks.
M R Corboz et al.
Pulmonary pharmacology & therapeutics, 20(2), 149-156 (2006-07-01)
Nasal congestion, one of the major disease features of rhinitis, is induced by the filling of venous sinusoids causing mucosal engorgement with resultant obstruction of nasal airflow. The only available drugs that directly target the underlying vascular features driving nasal
M R Corboz et al.
Pulmonary pharmacology & therapeutics, 21(3), 449-454 (2007-09-18)
The vascular bed in nasal mucosa of different species, including human, is highly vascularized and an extensive sinusoidal network of large capacitance vessels is present deep within the submucosa. When this network of venous sinusoids is engorged with blood, the
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service