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C4866

Sigma-Aldrich

Cardiogenol C hydrochloride

≥97% (HPLC), solid

Synonym(s):

4-(2-Hydroxyethylamino)-2-(4-methoxyphenylamino)-pyrimidine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C13H16N4O2 ·HCl
CAS Number:
671225-39-1
Molecular Weight:
296.75
MDL number:
MFCD06798334
UNSPSC Code:
51111800
PubChem Substance ID:
24724440
NACRES:
NA.32

assay

≥97% (HPLC)

form

solid

mol wt

296.75

packaging

pkg of 5 mg

solubility

H2O: soluble 10 mg/mL

storage temp.

−20°C

SMILES string

Cl[H].COc1ccc(Nc2nccc(NCCO)n2)cc1

InChI

1S/C13H16N4O2.ClH/c1-19-11-4-2-10(3-5-11)16-13-15-7-6-12(17-13)14-8-9-18;/h2-7,18H,8-9H2,1H3,(H2,14,15,16,17);1H

InChI key

QQAHYSZVJLHCNA-UHFFFAOYSA-N

Biochem/physiol Actions

Cardiogenol C hydrochloride is a cardiomyogenesis inducer in embryonic stem cells.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Xu Wu et al.
Journal of the American Chemical Society, 126(6), 1590-1591 (2004-02-12)
A phenotypic cell-based screen of a large combinatorial chemical library led to the identification of a class of diaminopyrimidine compounds (cardiogenol A-D) which can selectively and efficiently induce mouse embryonic stem cells (ESCs) to differentiate into cardiomyocytes. ESC-derived cardiomyocytes were

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