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CLS4514

Corning® 384 well microplate, low volume

surface treatment, Non-binding Surface, black polystyrene, U-bottom, non-sterile, lid: no, pack of 10

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Synonym(s):
Corning® 384 well microplate, low volume | Sigma-Aldrich
NACRES:
NB.24

material

U-bottom
black bottom
black polystyrene

sterility

non-sterile

feature

lid: no
skirt
U-bottom (black)

packaging

pack of 10

manufacturer/tradename

Corning 4514

well volume

35 μL

wells

384 wells , low volume

working volume

2-20 μL

binding type

NBS (non-binding surface)

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General description

The Corning® 384-well microplate, low volume has a skirted, U-bottom design and black polystyrene material. The black walls minimize crosstalk, background luminescence, and fluorescence, resulting in improved luminescent signals. The nonbinding surface (NBS) technology helps reduce molecular interactions at low concentrations thereby increasing assay signal to noise ratio.

Application

Corning®384 well microplate has been used for lowering nucleic acid and protein binding at low concentrations while enhancing the assay signal-to-noise ratio.

Features and Benefits

  • It has a square well that makes robotic pipetting more convenient
  • Rounded bottom to reduce trapped air and increased Z factor
  • For efficiency, a light cone-shaped conical well is used
  • During fluorescent experiments, the presence of opaque walls diminishes autofluorescence and crosstalk between wells
  • Microplates have non-ionic hydrophilic surfaces as a result of nonbinding surface technology treatment, which reduces molecular interactions

Legal Information

Corning is a registered trademark of Corning, Inc.
NBS is a trademark of Corning, Inc.

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Protocols

Jump dilution protocol to determine the residence time of a drug (or drug candidate) during its interaction with a kinase using a fluorescence polarization assay based on the detection of ADP.

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