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D3664

Sigma-Aldrich

Deoxyribonucleic acid sodium salt from calf thymus

suitable for substrate for DNase (Readily soluble)

Synonym(s):

CT-DNA, calf thymus DNA, DNA sodium salt from calf thymus, Thymonucleic acid sodium salt

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About This Item

CAS Number:
73049-39-5
MDL number:
MFCD00130922
UNSPSC Code:
41106305
eCl@ss:
32160414
NACRES:
NA.51

form

powder or crystals

Quality Level

200

suitability

suitable for substrate for DNase (Readily soluble)

storage temp.

2-8°C

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Application

Calf thymus DNA (CT-DNA) is a natural DNA widely used in studies of DNA binding anticancer agents and DNA binding agents that modulate DNA structure and function. Calf thymus DNA is also used in physicochemical studies of DNA behavior in solution.

Packaging

Preweighed vials prepared from D1501

related product

Product No.
Description
Pricing

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000420923
0000421396
0000421396
0000420923
0000399414

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Xingyi Chen et al.
Molecular pharmaceutics, 16(6), 2690-2699 (2019-05-01)
The nucleotide-binding domain and leucine-rich repeat-containing family, pyrin domain-containing 3 (NLRP3) inflammasome is a key regulator of innate immune responses, and its aberrant activation is implicated in the pathogenesis of many diseases such as Alzheimer's disease and type 2 diabetes.
Abdollah Zakeri Siavashani et al.
Biomaterials science, 8(1), 148-162 (2019-10-31)
Implantation of temporary and permanent biomaterials in the body leads to a foreign body reaction (FBR), which may adversely affect tissue repair processes and functional integration of the biomaterial. However, modulation of the inflammatory response towards biomaterials can potentially enable
Kristin Grøsvik et al.
Frontiers in microbiology, 11, 263-263 (2020-03-12)
The cellular methyl donor S-adenosylmethionine (SAM) and other endo/exogenous agents methylate DNA bases non-enzymatically into products interfering with replication and transcription. An important product is 3-methyladenine (m3A), which in Escherichia coli is removed by m3A-DNA glycosylase I (Tag) and II
Zhenjia Liu et al.
Chemotherapy, 57(4), 310-320 (2011-09-07)
Phenanthroindolizidine alkaloids are a family of plant-derived compounds with significant antineoplastic activity. The specific biomolecular targets of these alkaloids have not yet been clearly identified. (+)-(13aS)-deoxytylophorinine is a new phenanthroindolizidine alkaloid originally extracted from the roots of Tylophora atrofolliculata and
Farhad Ahmadi et al.
DNA and cell biology, 31(2), 259-268 (2011-08-25)
In this work, multispectroscopic atomic force microscopy and molecular modeling [ONIOM 2(B3LYP/6-31++G(d,p): Universal Force Field (UFF)) level] techniques were used to study the interaction between Calf-Thymus-DNA (CT-DNA) and pyriproxyfen (PYR) insecticide. The binding constant of PYR with double-strand deoxyribonucleic acid
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Protocols

Enzymatic Assay of Deoxyribonuclease I (EC 3.1.21.1)

To standardize a procedure for the enzymatic assay of Deoxyribonuclease I.

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