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E1625

Sigma-Aldrich

Elastin from bovine neck ligament

powder

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CAS Number:
EC Number:
MDL number:
NACRES:
NA.61

biological source

bovine neck ligament

Quality Level

form

powder

UniProt accession no.

storage temp.

2-8°C

InChI

1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1

InChI key

DPUYCSDGMSDKKV-MKBYFEBXSA-N

Gene Information

cow ... ELN(280781)

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This Item
E6527L6385T1001
vibrant-m

E1625

Elastin from bovine neck ligament

vibrant-m

L6385

α-Lactalbumin from bovine milk

vibrant-m

T1001

Thyroglobulin from bovine thyroid

form

powder

form

salt-free, lyophilized powder

form

powder

form

powder

Gene Information

cow ... ELN(280781)

Gene Information

cow ... ELN(280781)

Gene Information

cow ... LALBA(281894)

Gene Information

cow ... TG(280706)

UniProt accession no.

P04985

UniProt accession no.

P04985

UniProt accession no.

P00711

UniProt accession no.

P01267

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

Application

Elastin is a structural protein which has been used in studies of Chronic obstructive pulmonary disease (COPD). It may be used to investigate why there is a lack of repair for these proteins in patients with COPD.
Highly stable and hemocompatible protein now finding use in construction of biomaterials as a result of several strategies for its solubilization.

Biochem/physiol Actions

Protein responsible for the elasticity of many tissues. It is especially important in blood vessels, where it comprises about 50% of the dry tissue weight.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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H M Morrison et al.
Biochimica et biophysica acta, 1430(2), 179-190 (1999-03-20)
Solubilization of elastin by human leukocyte elastase (HLE) cannot be analyzed by conventional kinetic methods because the biologically relevant substrate is insoluble and the concentration of enzyme-substrate complex has no physical meaning. We now report quantitative measurements of the binding
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Oxidative stress is associated with photoaging of the skin as well as with skin cancer, and is therefore, critical to monitor. Ultraweak photon emission (UPE) is extremely weak light generated during the oxidative process in the living body and has
N Vyavahare et al.
The American journal of pathology, 155(3), 973-982 (1999-09-17)
Elastin, an abundant structural protein present in the arterial wall, is prone to calcification in a number of disease processes including porcine bioprosthetic heart valve calcification and atherosclerosis. The mechanisms of elastin calcification are not completely elucidated. In the present
Isabella C P Rodrigues et al.
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Tubular polymer scaffolds based on tissue engineering techniques have been studied as potential alternatives for vascular regeneration implants. The blood vessels of the cardiovascular system are mainly fibrous, composed of collagen (Col) and elastin (El), and its inner layer consists
Xiaozhuo Shao et al.
Journal of biomedical optics, 16(6), 067005-067005 (2011-07-05)
The aim of this study is to evaluate the biochemical foundation and clinical capability of an image-guided near-infrared (NIR) autofluorescence (AF) spectroscopy technique for in vivo diagnosis of colonic malignancies during clinical colonoscopy. A novel endoscopic fiber-optic AF system was

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