E4786

Escitalopram oxalate

≥98% (HPLC), powder, serotonin reuptake inhibitor

• Synonym(s): S-(+)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate, S-(+)-Citalopram oxalate
• Empirical Formula (Hill Notation): C₂₀H₂₁FN₂O · C₂H₂O₄
• CAS Number: 219861-08-2
• Molecular Weight: 414.43
• MDL number: MFCD06407826
• UNSPSC Code: 12352200
• PubChem Substance ID: 329799062
• NACRES: NA.77

Properties

• product name: Escitalopram oxalate, ≥98% (HPLC), powder
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to tan
• solubility: DMSO: ≥15 mg/mL
• originator: Forest Labs
• storage temp.: 2-8°C
• SMILES string: OC(=O)C(O)=O.CN(C)CCC[C@]1(OCc2cc(ccc12)C#N)c3ccc(F)cc3
• InChI: 1S/C20H21FN2O.C2H2O4/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;3-1(4)2(5)6/h4-9,12H,3,10-11,14H2,1-2H3;(H,3,4)(H,5,6)/t20-;/m0./s1
• InChI key: KTGRHKOEFSJQNS-BDQAORGHSA-N
• Gene Information: human ... SLC6A4(6532)

Description

General description

Escitalopram oxalate is an anti-depressant. It is used to treat panic disorder and major depressive disorder(MDD).

Application

Escitalopram oxalate has been used as an antidepressant in rats exposed to chronic mild stress (CMS). It has also been used for scintillation proximity-based thermostability assay.

Biochem/physiol Actions

Escitalopram is a selective serotonin reuptake inhibitor (SSRI), the S-enantiomer and eutomer of citalopram.

Features and Benefits

This compound was developed by Forest Labs. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312
• pcodes: P264 - P280 - P301 + P312 - P302 + P352 + P312 - P362 + P364 - P501
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable