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EHU015751

Sigma-Aldrich

MISSION® esiRNA

targeting human FBN1

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NACRES:
NA.51

description

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Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TTTGCACTAATGCCTGACCAGAGATCATGCACCGACATCGATGAGTGTGAAGATAATCCCAATATCTGTGATGGTGGTCAGTGCACAAATATCCCTGGAGAGTACAGGTGCTTGTGTTATGATGGATTCATGGCATCTGAAGACATGAAGACTTGTGTAGATGTCAATGAGTGTGACCTGAATCCAAATATCTGCCTAAGTGGGACCTGTGAAAACACGAAAGGCTCATTTATCTGCCACTGTGATATGGGCTACTCCGGCAAAAAAGGAAAAACTGGCTGTACAGACATCAATGAATGTGAAATTGGAGCACACAACTGTGGCAAACATGCTGTATGTACCAATACAGCAGGAAGCTTCAAATGTAGCTGCAGTCCCGGGTGGATTGGAGATGGCATTAAGTGCACTGATCTGGACGAATGTTCCA

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

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EHU041791EHU055461EHU108921
MISSION® esiRNA targeting human FBN1

EHU015751

MISSION® esiRNA

MISSION® esiRNA targeting human FBN2

EHU041791

MISSION® esiRNA

MISSION® esiRNA targeting human FCER1G

EHU055461

MISSION® esiRNA

MISSION® esiRNA targeting human FDX1

EHU108921

MISSION® esiRNA

Ensembl | human accession no.

ENSG00000166147

Ensembl | human accession no.

ENSG00000138829

Ensembl | human accession no.

ENSG00000158869

Ensembl | human accession no.

ENSG00000137714

esiRNA cDNA target sequence

TTTGCACTAATGCCTGACCAGAGATCATGCACCGACATCGATGAGTGTGAAGATAATCCCAATATCTGTGATGGTGGTCAGTGCACAAATATCCCTGGAGAGTACAGGTGCTTGTGTTATGATGGATTCATGGCATCTGAAGACATGAAGACTTGTGTAGATGTCAATGAGTGTGACCTGAATCCAAATATCTGCCTAAGTGGGACCTGTGAAAACACGAAAGGCTCATTTATCTGCCACTGTGATATGGGCTACTCCGGCAAAAAAGGAAAAACTGGCTGTACAGACATCAATGAATGTGAAATTGGAGCACACAACTGTGGCAAACATGCTGTATGTACCAATACAGCAGGAAGCTTCAAATGTAGCTGCAGTCCCGGGTGGATTGGAGATGGCATTAAGTGCACTGATCTGGACGAATGTTCCA

esiRNA cDNA target sequence

GCAGGATGCAAATGGAGATTGTATAGATGTTGATGAATGCACATCAAATCCCTGCACTAATGGAGATTGTGTTAACACACCTGGTTCCTATTATTGTAAATGTCATGCTGGATTCCAGAGGACTCCTACCAAGCAAGCATGCATTGATATTGATGAGTGCATCCAGAATGGGGTTCTTTGTAAAAACGGTCGATGCGTGAACACAGATGGAAGTTTCCAGTGCATTTGCAATGCCGGCTTTGAATTAACTACAGATGGAAAAAACTGTGTTGATCATGATGAATGTACAACTACCAACATGTGTTTGAATGGAATGTGCATCAATGAAGATGGCAGCTTCAAGTGCATCTGCAAACCAGGATTTGTCTTGGCTCCAAATGGGCGTTACTGTACTGATGTTGATGAATGCCAGACCCCAGGAATCTGCATGAATGGGCACTGCATCAACAGTGAAGGGTCCTTCC

esiRNA cDNA target sequence

GGAGAGCCTCAGCTCTGCTATATCCTGGATGCCATCCTGTTTCTGTATGGAATTGTCCTCACCCTCCTCTACTGTCGACTGAAGATCCAAGTGCGAAAGGCAGCTATAACCAGCTATGAGAAATCAGATGGTGTTTACACGGGCCTGAGCACCAGGAACCAGGAGACTTACGAGACTCTGAAGCATGAGAAACCACCACAGTAGCTTTAGAATAGATGCGGTCATATTCTTCTTTGGCTTCTGGTTCTTCCAGCCCTCATGGTTGGCATCACATATGCCTGCATGCCATTAACACCAGCTGGCCCTACCCCTATAATGATCCTGTGTCCTAAATTAATATACACCAGTGGTTCCTCCTCCCTGTTAAAGACTAATGCTCAGATGCTGTTTACGG

esiRNA cDNA target sequence

CCGGAGCAGCTCAGAAGATAAAATAACAGTCCACTTTATAAACCGTGATGGTGAAACATTAACAACCAAAGGAAAAGTTGGTGATTCTCTGCTAGATGTTGTGGTTGAAAATAATCTAGATATTGATGGCTTTGGTGCATGTGAGGGAACCCTGGCTTGTTCAACCTGTCACCTCATCTTTGAAGATCACATATATGAGAAGTTAGATGCAATCACTGATGAGGAGAATGACATGCTCGATCTGGCATATGGACTAACAGACAGATCACGGTTGGGCTGCCAAATCTGTTTGACAAAATCTATGGACAATATGACTGTTCGAGTGCCTGAAACAGTGGCTGATGCCAGACAATCCATTGATGTGGGCAAGACCTCCTGAACTAGAACAAATAGGAATATTTTCATGGAATTTTACCTATTTTTATAATTATTATTTCTTAAAGTGATTAAATGAGAACATGGATGAGTGGACTTCA

Gene Information

human ... FBN1(2200), FBN1(2200)

Gene Information

human ... FBN2(2201), FBN2(2201)

Gene Information

human ... FCER1G(2207), FCER1G(2207)

Gene Information

human ... FDX1(2230), FDX1(2230)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

NCBI accession no.

NM_000138

NCBI accession no.

NM_001999

NCBI accession no.

NM_004106

NCBI accession no.

NM_004109

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable


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Ziliang Wang et al.
Oncotarget, 6(9), 6670-6683 (2015-03-10)
While Aurora-A (Aur A) provokes, BRCA2 restrains primary tumorigenesis, the roles of Aur A and BRCA2 in cancer metastasis remains unclear. Here, we show that the metastatic promoting markers SLUG, FBN1, and MMP2, 9, 13 are either stimulated or suppressed
Kai Huang et al.
Redox biology, 38, 101757-101757 (2020-10-31)
In the present study we aimed to identify novel mechanisms and therapeutics for thoracic aortic aneurysm (TAA) in Fbn1C1039G/+ Marfan Syndrome (MFS) mice. The expression of mature/active TGFβ and its downstream effector NOX4 were upregulated while tetrahydrobiopterin (H4B) salvage enzyme

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